In view of an emerging consensus on how Alzheimer’s disease develops and progresses, the Cure Alzheimer’s Fund Research Consortium aggressively is focusing on three opportunities for possible intervention—at the early stage of the disease, the middle stage and the late stage. This comprehensive strategy addresses the whole picture of how Alzheimer’s disease develops and progresses, and attacks all three points simultaneously.
When Dr. Thomas Südhof first learned he had won the Nobel Prize last October, he could not have been more surprised. “Are you serious?” were the first words out of his mouth.
For PBS's series "The Secret Life of Scientists and Engineers", Rudy Tanzi, Ph.D., talks about his life-long love of music.
A stem cell model of familial Alzheimer’s disease (FAD) was successfully generated in a recent study, allowing researchers to identify 14 genes potentially implicated in the disease. One gene in particular demonstrates the important role inflammation may play in the brain of Alzheimer’s patients. The study was completed by scientists at The New York Stem Cell Foundation (NYSCF) Research Institute in collaboration with scientists at the Icahn School of Medicine at Mount Sinai (ISMMS) and funded in part by the Cure Alzheimer’s Fund (CAF).
Scientists at The New York Stem Cell Foundation (NYSCF) Research Institute, working in collaboration with scientists from Columbia University Medical Center (CUMC), for the first time generated induced pluripotent stem (iPS) cells lines from non-cryoprotected brain tissue of patients with Alzheimer’s disease.
On Saturday, January 4, Rudy Tanzi, Ph.D. appeared on CBS News' This Morning to discuss the current state of research towards an Alzheimer's cure.
In the segment, Tanzi explains some of the reasons behind past drug failures and the ways in which the current generation of drugs in development will hopefully avoid these pitfalls. He also describes preventative measures one can take against the disease, such as healthy diet, exercise, and social engagement.
Brain aging is associated with lower production of circadian clock proteins, which synchronize biological processes to light and dark cycles. In Alzheimer’s and other neurodegenerative diseases, circadian dysfunction is commonly observed.
Several weeks ago, the Cure Alzheimer’s Fund (CAF) Executive Committee and staff met with the members of our Research Consortium in Chicago.
Adding to its impressive roster of many of the nation’s leading scientists, the Cure Alzheimer’s Fund Research Consortium is pleased to announce its two newest members, Eric Schadt, Ph.D. (left), and Rick Huganir, Ph.D. (right).
The Research Consortium develops and updates a “roadmap for research” for the most effective and efficient route to slowing, stopping and/or reversing Alzheimer’s disease, the most common form of dementia. Members research their own projects and recruit others whose work will hasten the development of effective therapies.
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