A stem cell model of familial Alzheimer’s disease (FAD) was successfully generated in a recent study, allowing researchers to identify 14 genes potentially implicated in the disease. One gene in particular demonstrates the important role inflammation may play in the brain of Alzheimer’s patients. The study was completed by scientists at The New York Stem Cell Foundation (NYSCF) Research Institute in collaboration with scientists at the Icahn School of Medicine at Mount Sinai (ISMMS) and funded in part by the Cure Alzheimer’s Fund (CAF).
Scientists at The New York Stem Cell Foundation (NYSCF) Research Institute, working in collaboration with scientists from Columbia University Medical Center (CUMC), for the first time generated induced pluripotent stem (iPS) cells lines from non-cryoprotected brain tissue of patients with Alzheimer’s disease.
On Saturday, January 4, Rudy Tanzi, Ph.D. appeared on CBS News' This Morning to discuss the current state of research towards an Alzheimer's cure.
In the segment, Tanzi explains some of the reasons behind past drug failures and the ways in which the current generation of drugs in development will hopefully avoid these pitfalls. He also describes preventative measures one can take against the disease, such as healthy diet, exercise, and social engagement.
Brain aging is associated with lower production of circadian clock proteins, which synchronize biological processes to light and dark cycles. In Alzheimer’s and other neurodegenerative diseases, circadian dysfunction is commonly observed.
Adding to its impressive roster of many of the nation’s leading scientists, the Cure Alzheimer’s Fund Research Consortium is pleased to announce its two newest members, Eric Schadt, Ph.D. (left), and Rick Huganir, Ph.D. (right).
The Research Consortium develops and updates a “roadmap for research” for the most effective and efficient route to slowing, stopping and/or reversing Alzheimer’s disease, the most common form of dementia. Members research their own projects and recruit others whose work will hasten the development of effective therapies.
Washington (November 7, 2013) – As the country commemorates November as National Alzheimer’s Awareness month, Senator Edward J. Markey (D-Mass.) has been announced as the new Senate co-chair of the Bipartisan Congressional Task Force on Alzheimer’s Disease. Senator Markey was co-chair of the Task Force with Rep. Chris Smith (R-N.J.) when he served in the House of Representatives. While in the House, then-Rep. Markey co-authored the National Alzheimer’s Project Act, which mandated the development of a first-ever comprehensive National Plan to Address Alzheimer’s Disease.
Our congratulations to Dr. Thomas C. Sϋdhof of Stanford University, a member of Cure Alzheimer’s Fund's Research Consortium, who joins Randy Scheckman of the University of California, Berkeley and James E. Rothman of Yale University in winning the Nobel Prize in Physiology or Medicine as announced today.