Selected Publications

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Schjeide BM, Hooli B, Parkinson M, Hogan MF, DiVito J, Mullin K, Blacker D, Tanzi RE, Bertram L , "GAB2 as an Alzheimer Disease Susceptibility Gene, Follow up of Genomewide Association Results" , Arch Neurol , 66 , Feb 2009 , 250 – 254
Bertram L, Schjeide BM, Hooli B, Mullin K, Hiltunen M, Soininen H, Ingelsson M, Lannfelt L, Blacker D, Tanzi RE. , "No association between CALHM1 and Alzheimer's disease risk." , Cell , 135(6) , Dec 12 2008 , 993-4
Xie Z, Culley DJ, Dong Y, Zhang G, Zhang B, Moir RD, Frosch MP, Crosby G, Tanzi RE.  , "The common inhalation anesthetic isoflurane induces caspase activation and increases Aβ level in vivo." , Annals of Neurology , Volume 64 , Dec 2008
Cotton RG, Auerbach AD, Axton M, Barash CI, Berkovic SF, Brookes AJ, Burn J, Cutting G, den Dunnen JT, Flicek P, Freimer N, Greenblatt MS, Howard HJ, Katz M, Macrae FA, Maglott D, Möslein G, Povey S, Ramesar RS, Richards CS, Seminara D, Smith TD, Sobrido MJ, Solbakk JH, Tanzi RE, Tavtigian SV, Taylor GR, Utsunomiya J, Watson M , "The Human Variome Project" , Science. , 322(5903) , Nov 7 2008 , 861-2
Bertram L, Lange CL, Mullin K, Parkinson M, Hsiao M, Hogan MF,  Schjeide BMM, Hooli B, DeVito J, Ionita I, Jiang H, Laird N, Moscarillo T, Ohlsen KL, Elliott K, Wang X, Hu-Lince D, Ryder M, Murphy A, Wagner SL, Blacker D, Becker KD, Tanzi RE. , "Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE" , Am. J. Hum. Genet. , 83 , November 2008 , 623-632
Bertram L, Tanzi RE , "Thirty years of Alzheimer’s disease genetics: the implications of systematic meta-analyses" , Nature Reviews Neurosci. , October 2008
Schaffer B, Bertram L, Miller L, Mullin K, Weintraub S, Johnson N, Bigio E, Mesulam M, Wiedau-Pazos M, Jackson G, Cummings J, Cantor R, Levey A, Tanzi RE, and Geschwind D , "Association of GSK3B with Alzheimer's Disease and Frontotemporal Dementia" , Arch. Neurol. , 65(10) , October 2008 , 1368-1374
Zhang B, Dong Y, Zhang G, Moir RD, Xia W, Yue Y, Tian M, Culley DJ, Crosby G, Tanzi RE, Xie Z , "The inhalation anesthetic desflurane induces caspase activation and increases amyloid-beta protein levels under hypoxic conditions." , J Biol Chem. , 2;283(18) , May 2, 2008 , 11866-75
Zhang G, Dong Y, Zhang B, Ichinose F, Wu X, Culley DJ, Crosby G, Tanzi RE, Xie Z. , "Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine." , J Neurosci , 28 , April 23, 2008 , 4551-60
Tesco G, Koh YH, Kang E, Cameron A, Das S, Sena-Esteves M, Hiltunen, Yang S-H, Zhong Z, Shen Y, Simpkins J, Tanzi RE. , "Depletion of GGA3 stabilizes BACE and enhances β-secretase activity" , Neuron , 54(5) , 2007 , 721-37
Kim M, Hersh LB, Leissring MA, Ingelsson M, Matsui T, Farris W, Lu A, Hyman BT, Selkoe DJ, Bertram L, Tanzi RE , "Decreased catalytic activity of the insulin degrading enzyme in chromosome 10-linked Alzheimer’s disease families." , Journal of Biological Chemistry , 282(11) , 2007 , 7825-32
Xie Z, Dong Y, Maeda U, Moir R, Xia W, Culley DJ, Crosby G, Tanzi RE. , "The Inhalation Anaesthetic Isoflurane Induces a Vicious Cycle of Apoptosis and Aβ Accumulation." , J. Neurosci. , 27 , 2007 , 1247-1254
McQueen MB, Bertram L, Lange C, Becker KD, Albert MS, Tanzi RE, Blacker D. , "Exploring Candidate Gene Associations with Neuropsychological Performance." , Am J Med Genet B Neuropsychiatr Genet , 144(8) , 2007 , 987-91