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George S. Bloom, Ph.D.
Professor of Biology and Cell Biology, University of Virginia
Associate Editor, Cytoskeleton
Dr. Bloom obtained his Bachelor of Arts degree from the University of Pennsylvania in 1973 and his Ph.D. from the University of Pennsylvania in 1979. He then completed two postdoctoral fellowships: from 1979–1980 at the University of North Carolina’s Cancer Research Center, and from 1980–1984 at the Worcester Foundation for Experimental Biology, where his longstanding interest in neuronal cell biology was initiated in the laboratory of Dr. Richard Vallee. After finishing his postdoctoral training in 1984, Dr. Bloom joined the faculty of the Department of Cell Biology at the University of Texas Southwestern Medical Center, where he remained until his move to the University of Virginia in 2000.
Project Description Researchers Funding Structural and Functional Analysis of Novel Abeta and Tau Oligomers Using Conformation-Specific Monoclonal Antibodies
The goal of this project is to determine which oligomers of Abeta and Tau are most damaging and whether specific antibodies can prevent formation of those oligomers.
George S. Bloom, Ph.D. 2011
These published papers resulted from Cure Alzheimer’s Fund support."Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β" , Nature , 485 , May 2, 2012 , 651-655,