William Mobley, MD, Ph.D.

Headshot photo

Distinguished Professor and Chair of the Department of Neurosciences at University

of California at San Diego

Executive Director of UCSD's Down Syndrome Center for Research and Treatment

Dr. Mobley came to UCSD in June 2009 from Stanford University in Palo Alto, Calif., where he served as the John E. Cahill Family Professor in the Department of Neurology and Neurological Sciences and was the founding director of the Neuroscience Institute. Dr. Mobley is the recipient of both the Zenith Award and the Temple Award from the Alzheimer’s Association and was chosen to receive the Cotzias Award of the American Academy of Neurology in 2004. Dr. Mobley is Past President of the Association of University Professors of Neurology, of the Professors of Child Neurology, and of the International Society for Developmental Neuroscience.  He is a Fellow of the Royal College of Physicians and in 2006 was named a Fellow of the American Association for the Advancement of Science.

Funded Research

Project Description Researchers Funding
Design, Synthesis and Characterization of Novel and Potent Gamma Secretase Modulators: Physiochemical and Pharmacokinetic Properties

During the past year, our laboratory at UCSD (Wagner laboratory), in close collaboration with the Tanzi laboratory at MGH, discovered, synthesized and characterized (in vitro) a novel series of molecules able to potently prevent the formation of what is currently thought to be the pathogenic culprit of Alzheimer’s disease (AD).
Steve Wagner, Ph.D.
William Mobley, MD, Ph.D.
 2009
$200,000