Modern science has an incredibly thorough understanding of the human body. It is hard to imagine that any organ or system could exist within the body that has yet to be discovered. Yet this is exactly what happened in 2015, when researchers discovered lymphatic vessels around and within the brain.
It may not be surprising to learn that brain health is intricately linked to the state of the rest of the body. But what are the links, and what role do these connections play in diseases like Alzheimer’s? Sam Sisodia, Ph.D., of the University of Chicago, is examining one of the most important connections: the way in which our gut microbiome influences the brain in Alzheimer’s disease.
(CHICAGO, IL) – OCTOBER 7, 2016 – Rotary and Cure Alzheimer’s Fund today announced an agreement to co-fund a new, groundbreaking research project to search for female-specific genetic and other factors contributing to women’s risk for Alzheimer’s disease. In total, the two organizations will provide a grant of $375,000 for this critical research.
What do the developing brain and the Alzheimer’s brain have in common? Beth Stevens, Ph.D., a developmental neurologist, is investigating an important connection: the loss of synapses, where neurons connect with one another to transmit important signals.
New evidence—funded by Cure Alzheimer’s Fund (CAF) and others—has emerged suggesting a strong connection between air pollution and Alzheimer’s disease. “These findings underscore the complexity of this disease,” says CAF President and CEO Tim Armour, “and emphasize the need for a comprehensive approach to stop it.”
Building on its enormously successful “Whole Genome Sequencing” Project, which identified nearly 1,000 new genetic mutations in more than 50 different genes, Cure Alzheimer's Fund has announced a new, even more ambitious multiyear, $50 million plus program titled “Genes to Therapies” (G2T). Simply put, the new project’s goal is to use the most promising recent genetic discoveries to develop drugs that would stop the disease at three separate stages: