Bart De Strooper is a professor of molecular medicine at the University of Leuven and University College London. He leads research groups at the VIB Centre for Brain and Disease research in Leuven, Belgium, Ā and at the Crick Institute in London. Bart De Strooperās scientific work is focused on the understanding ...
August 9, 2016
Recent studies from the laboratory of Dr. Gary Landreth (Cramer P. et. al (2012) Science 335) have demonstrated that Bexarotene (Targretin), a highly selective, blood-brain barrier-permeant, FDA-approved, RXR agonist for the treatment of cutaneous T-cell lymphoma, can rapidly reduce amyloid plaque burden and rescue behavioral deficits in transgenic mouse models ...
December 12, 2012
The goal of this project is to investigate the mechanisms through which RXRs (retinoid x nuclear receptor) promote amyloid clearance from the brain. There is now persuasive evidence that sporadic, late-onset forms of AD arise from impaired clearance of Abeta from the brain. Moreover, the elevated risk associated with possession of ...
November 11, 2011
Findings from Cure Alzheimerās Fund Help Drive the Alzheimerās Initiative āAlzheimerās takes a devastating toll on millions of Americans,ā said Kathleen Sebelius, secretary of Health and Human Services. āItās a very important health issue. The time for bold action is right now.ā We at Cure Alzheimerās Fund are delighted by todayās announcement ...
February 7, 2012
January 30, 2024
February 8, 2024
2019 This project recently established a more accurate and efficient model to identify fluorescent images generated by treating the Alzheimerās in a Dish model with compounds that can clear accumulated phosphorylated tau. Meanwhile, 29 new candidate compounds recently going through clinical trials for various diseases were generated by in silico prediction ...
August 27, 2018
Nation’s largest puzzle maker will donate percentage of sales from Puzzles to Remember product line to support Alzheimer’s research WELLESLEY, Mass.,Ā July 27, 2017 āĀ Cure Alzheimer’s FundĀ announced today that it has partnered withĀ Kansas City-based puzzle manufacturerĀ Springbok Puzzles.Ā Springbok has created a line of jigsaw puzzles ā Puzzles to Remember ā specifically designed for ...
July 27, 2017
Cure Alzheimerās Fund (CureAlz) has received a $50,000 grant from the Robert A. Stranahan, Jr. Charitable Advised Fund of the Greater Toledo Community Foundation. This grant represents their largest gift to Cure Alzheimerās Fund since the Robert A. Stranahan, Jr. Charitable Advised Fund made its first grant to the non-profit in ...
November 13, 2023
You are invited to participate in an exclusive Catalyst Society Video Conference with a member of the Cure Alzheimerās FundĀ Research Consortium. David Michael Holtzman, M.D.Ā will share new insights about the disease pathologyĀ and the opportunities and challenges facing the Alzheimerās scientific research community. The presentation will be followed by a Q&A. If we ...
May 4, 2017
