Alterations of human CSF and serum-based mitophagy biomarkers in the continuum of Alzheimer disease

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Climbing the World to End Alzheimer’s

Please join David Shenk and Alan Arnette for our free, one-hour upcoming webinar, Climbing the World to End Alzheimer’s, on July 24th at 2:30 pm EDT. Arnette became an Alzheimer’s caregiver and advocate when his mother, Ida, was diagnosed. He felt compelled to make a difference in the world of Alzheimer’s ...

June 28, 2012

Alzheimer’s secretases regulate voltage-gated sodium channels

January 30, 2024

Doo Yeon Kim, Dora M. Kovacs, retired

Infection and inflammation: New perspectives on Alzheimer’s disease

April 22, 2022

Alison Goate, Beth Stevens, David M. Gate, Rudolph Tanzi, Sangram S. Sisodia

Assessment of the In Vivo Relationship Between Cerebral Hypometabolism, Tau Deposition, TSPO Expression, and Synaptic Density in a Tauopathy Mouse Model: a Multi-tracer PET Study

January 30, 2024

Eckhard Mandelkow, Eva-Maria Mandelkow

Mast cell deficiency improves cognition and enhances disease-associated microglia in 5XFAD mice

January 30, 2024

Fanny Herisson, Rudolph Tanzi

Lysosomal enzyme tripeptidyl peptidase 1 destabilizes fibrillar A beta by multiple endoproteolytic cleavages within the beta-sheet domain

January 30, 2024

Frederick Maxfield

A shortened Barnes Maze Protocol reveals memory deficits at 4-months of age in the triple-transgenic mouse model of Alzheimer’s disease

January 30, 2024

Gal Bitan

Cre-inducible Adeno Associated Virus-mediated Expression of P301L mutant tau causes motor deficits and neuronal degeneration in substantia nigra

January 30, 2024

Tsuneya Ikezu

TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss

January 30, 2024

Lawrence Rajendran