Genome-wide association studies in Alzheimer’s Disease

January 30, 2024

Lars Bertram, Rudolph Tanzi

APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice

January 30, 2024

Karen Duff, Tal Nuriel

APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading

July 17, 2023

David Holtzman, Erik S. Musiek, Jason D. Ulrich

Assessment of separation methods for extracellular vesicles from human and mouse brain tissues and human cerebrospinal fluids

January 30, 2024

Tsuneya Ikezu, Weiming Xia

Disrupting self-assembly and toxicity of amyloidogenic protein oligomers by “molecular tweezers” — from the test tube to animal models

January 30, 2024

Gal Bitan

Distinguishing true from false positives in genomic studies: p values

January 30, 2024

Lars Bertram

Living with Faith, Hope & Humor: The Hope For a Cure

As you cross the Sagamore Bridge over the Cape Cod Canal, heading to the mainland, the view to the starboard is startling in its natural beauty, its expanse of sapphire shoreline, and soul-searching mood for deep reflection. On an incoming ocean tide, the roiling waters of the canal spill out ...

February 26, 2023

Low Evolutionary Selection Pressure in Senescence does not explain the persistence of amyloid-beta in the vertebrate genome

January 30, 2024

Robert Moir, Rudolph Tanzi

Three-Dimensional Models of the Human Brain Development and Disease

January 30, 2024

Daniel Irimia, Doo Yeon Kim, Mehdi Jorfi

A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro

January 30, 2024

Eckhard Mandelkow