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Revealing New Genes and Pathways at the Intersection of Lipotoxic and Genetic Risk for Alzheimer’s Disease

Complex diseases, including Alzheimer’s disease (AD), are caused by an interaction of genetic and environmental risk factors. Emerging genetic studies of late-onset AD implicate neuroimmune mechanisms and the brain’s resident immune cells, called microglia, in AD pathogenesis. In many cases, genetic risk factors only are revealed by an environmental trigger. ...

February 14, 2022

Anna Greka, Beth Stevens

SHOULD YOU FIND OUT IF YOU’RE AT RISK OF ALZHEIMER’S?

With a simple at-home genetics test, some people are learning they have a higher risk of Alzheimer’s. Can they do anything to prevent the disease? By Sumathi Reddy Updated July 15, 2019 9:14 am ET When Theresa Braymer can’t remember a word or name, she sometimes second-guesses herself. At 59, she is young to ...

October 6, 2019

Mark H. Tuszynski

Mark Tuszynski is a Professor of Neurosciences at the University of California, San Diego, and the Founding Director of the UCSD Translational Neuroscience Institute. He received his undergraduate and M.D. degrees from the University of Minnesota (Minneapolis), clinical training in neurology at Cornell University Medical Center in New York, and ...

July 12, 2016

Maureen Maresca

On Losing a Loved One: Something We All Share A Personal Perspective: Is death just the beginning? There’s something final about death. But is it really the end? Or is death just a beginning? Over time, in wrestling with the spiritual side, I’ve personally come to believe that death is the gateway—eternity for those of ...

December 7, 2021

Do the Math: Adds New Meaning to Mother’s Day

Do the math. You don’t have to be a genius. Yet the statistics are so staggering one can’t count on their fingers. “More than six million people in the United States now have Alzheimer’s disease—and it is estimated that four million (two-thirds) are women,” notes the Cure Alzheimer’s Fund (https://curealz.org/). And that ...

April 18, 2023

Kevin Rynearson

Dr. Rynearson is a Project Scientist in the Department of Neurosciences at the University of California, San Diego (UCSD) School of Medicine. He received his B.S. in Chemistry from San Diego State University. Subsequently, Dr. Rynearson earned his M.S. and Ph.D. in Chemistry at UCSD under the supervision of Dr. ...

February 21, 2023

Kevin Rynearson

Genes to Therapies: One Year Later

In just its first year of operation, Cure Alzheimer’s Fund’s ambitious new Genes to Therapies™ (G2T) research program has bloomed far beyond expectations. “We’re firing on all cylinders now,” says Research Consortium Chair Dr. Rudy Tanzi. “It’s exactly where we need to be headed to stop this disease.” In 2015, Cure Alzheimer’s ...

February 12, 2016

Senate Appropriations Committee’s Commitment To Alzheimer’s Research Wins Plaudits

Cure Alzheimer’s Fund Urges Congress to Pass Bill This Fall Boston—Praising lawmakers for recognizing the importance of finding a cure for Alzheimer’s Disease, Cure Alzheimer’s Fund commended the U.S. Senate Appropriations Committee for passing promising legislation with strong funding and language backing Alzheimer’s research.    “We applaud the Committee for their support ...

August 7, 2009

Alzheimer’s and Down Syndrome: Overlap and Opportunity

The world already is very familiar with both Alzheimer’s disease (AD), primarily a disease that occurs in the elderly, and Down syndrome (DS), a genetic condition present at birth. What many don’t realize is that these two conditions also overlap. By age 40, nearly all people born with Down syndrome ...

July 25, 2014