Revealing New Genes and Pathways at the Intersection of Lipotoxic and Genetic Risk for Alzheimer’s Disease
Complex diseases, including Alzheimer’s disease (AD), are caused by an interaction of genetic and environmental risk factors. Emerging genetic studies of late-onset AD implicate neuroimmune mechanisms and the brain’s resident immune cells, called microglia, in AD pathogenesis. In many cases, genetic risk factors only are revealed by an environmental trigger. ...
February 14, 2022