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Update from the Board: December 2009

Dear Friends, Why should you care about Alzheimer’s research? Currently, for every dollar spent on Alzheimer’s care, only a penny is spent working toward a cure. This is a bad equation for a disease that is estimated will cost well more than $100 billion in care (Medicare and Medicaid alone) in 2009.   Cure ...

January 4, 2010

Featured Researcher: Charles G. Glabe, Ph.D.

From the age of 2, when he disassembled his brother’s mechanical duck and his father praised him for his curiosity, Charlie Glabe was always interested in the way things work. In college he supported himself as a car mechanic, but found his true passion in scientific research. Today Charlie is ...

November 7, 2014

TREM2 ANTIBODIES REDUCE AD PATHOLOGY

Microglia are the innate immune cells that reside in the central nervous system and remove unwanted particles and debris from the brain. TREM2 is a receptor found on microglia and its activation increases amyloid beta uptake; the effect is therefore neuroprotective. An antibody designed to increase TREM2 activation has shown ...

October 7, 2022

Antibody Signature of Alzheimer’s Disease: Promise of an Early Diagnostic Test

A physician can’t cure what he can’t diagnose. The diagnosis of Alzheimer’s disease is based on the exclusion of several neurological syndromes, rather than directly testing for the disease of interest. This can be an inaccurate exercise in up to 20% of the cases. Promising biomarkers are being developed, such ...

January 31, 2013

Lucas Restrepo

Jeff Morby: The Answers Are Being Revealed

Several weeks ago, the Cure Alzheimer’s Fund (CAF) Executive Committee and staff met with the members of our Research Consortium in Chicago. The purpose of the meeting was to review the progress of the different researchers and to brainstorm with them, as we do every year, about what modifications we should make to our roadmap to ...

November 21, 2013