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Alzstream™ Webinar: Bringing Gamma Secretase Modulators to Trials

Find out about the exciting progress being made with gamma secretase modulators, a potential drug therapy for Alzheimer’s, in this one-hour webinar. Steven Wagner, Ph.D., principal investigator at UC San Diego’s Department of Neuroscience, talks to David Shenk, senior adviser, Cure Alzheimer’s Fund, about how the modulators work and what’s ...

September 16, 2016

Joan S. Sands

10/22/1929 – 11/16/2020   Joan Sonnenblum Sands, aged 91, died peacefully on November 16, 2020, in Sarasota, FL, after a long illness.  A 1950 graduate of Skidmore College with a Bachelor of Arts degree in English, Joan later earned a Masters Degree in Education from Fairfield University in Connecticut and spent more than 30 ...

November 16, 2020

Contribution of Skull Bone Marrow-Derived Cells to Alzheimer’s Disease

Alzheimer’s disease is the most common neurodegenerative disease in America, affecting more than 6 million people and robbing them of their memory and independence as they age. Furthermore, as the population gets older, the number of people with Alzheimer’s disease is expected to more than double in the next 30 years. ...

February 14, 2022

Jonathan Kipnis

Janet Weigand Carter

Janet Weigand Carter, 99, died at her home on March 17, 2022, after a slow decline in health. Lorna Janet, also known as “Nettie” in her childhood, was born on September 25, 1922, in the Township of Ashford, Fond du Lac County on a Wisconsin dairy farm, the daughter of ...

March 21, 2022

Better Your Brain

While we don't know yet how to prevent Alzheimer's disease, there are steps that you can take to improve the overall health of your brain.

September 24, 2017

GAMMA-SECRETASE MODULATORS FOR AD

Amyloid beta (Ab) is a key protein that forms into plaque bundles. It is cleaved from the larger amyloid precursor protein by gamma-secretase into shorter lengths (Ab37, Ab38) and longer lengths (Ab40, Ab42). The longer lengths of amyloid beta are more likely to clump together into toxic plaques. Clinical trials more ...

October 7, 2022

Albert J. Rossi

Albert “Al” John Rossi, 81, a two-year resident of Pasadena and previously of Odenton and Mechanicsville, MD, died on Tuesday, October 17, 2023, at Sadie’s Serenity Creekside in Pasadena from debility resulting from vascular dementia. Born June 12, 1942 in New York, to the late Albert L. and Rose (Paterno) ...

November 28, 2023

Norman Grimshaw

Norman Charles Grimshaw of Glenview, IL, died peacefully on January 21, 2022.  He was 86 years old. His wife of 62 years, Maryellen Shepler Grimshaw, preceded him in death in July of 2021. He is survived by his four children: David, Suellen, James, and Sally, their spouses, nine grandchildren, and ...

January 25, 2022

Contribution of Skull Bone Marrow-Derived Cells to Alzheimer’s Disease

Alzheimer’s disease is the most common cause of dementia, impacting memory, thinking and behavior. It affects an estimated 32 million people worldwide, with one in 10 people older than 65 and nearly a third of people older than 85 having the disease. Alzheimer’s disease severely impacts a person’s ability to ...

December 8, 2023

Jonathan Kipnis

2-Deoxyglucose and Its Analogs as Novel Therapeutics to Build Resilience to Alzheimer’s Disease

Available evidence shows that pathological features of Alzheimer’s disease (AD) begin years before cognitive decline is clinically apparent. The insidious nature of AD evolution has focused attention on lifestyle approaches to build brain resilience and to forestall disease progression, even after symptom onset. Among important lifestyle influences, dietary approaches that ...

July 23, 2024

Rajiv R. Ratan, Theodore J. Lampidis