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Letter from the Founders – Why You Should Care About Alzheimer’s Research

Why should you care about Alzheimer’s research? Currently, for every dollar spent on Alzheimer’s care, only a penny is spent working toward a cure. This is a bad equation for a disease that is estimated to cost more than $100 billion in care (Medicare and Medicaid alone) in 2009. Cure Alzheimer’s Fund ...

December 10, 2009

Update from the Board: December 2009

Dear Friends, Why should you care about Alzheimer’s research? Currently, for every dollar spent on Alzheimer’s care, only a penny is spent working toward a cure. This is a bad equation for a disease that is estimated will cost well more than $100 billion in care (Medicare and Medicaid alone) in 2009.   Cure ...

January 4, 2010

TEAM BOOMERANGFIT

Boomerangfit is a group of Baby Boomers committed to getting back the fitness we once enjoyed in our 20s and 30s. There is no reason we need to succumb to the “normal” symptoms of age if we eat right, move, exercise, sleep, laugh, enjoy life and, most importantly, continue to ...

June 14, 2018

IMPACT CHARMS

The mission of Impact Charms is to educate their customers and supplement the charities they support with donations. These beautiful accessories feature artwork created to pay tribute to those who are affected by Alzheimer’s disease. Each piece is handmade in the United States by a team of senior citizens. The ...

October 30, 2020

Coconut Oil: A Scientific Perspective

Cure Alzheimer’s Fund has received many questions about the value of coconut oil in combatting Alzheimer’s. We’ve asked Rudy Tanzi, Ph.D., to respond to these inquiries generically, knowing that a) there is currently no peer-reviewed clinical research available regarding efficacy of coconut oil in treating or preventing Alzheimer’s, and b) ...

April 24, 2012

Development of Novel APP Dimerization Inhibitors That Lower Abeta Levels

Year 2 aims: Diseases that affect learning and memory are of fundamental biological importance and are among the most challenging biomedical problems of our time. We recently demonstrated that compounds that inhibit amyloid precursor protein (APP) dimerization and enhance APP phosphorylation reduce the levels of Abeta, the peptide responsible for the ...

September 29, 2015

Carmela R. Abraham

Optimization of Pharmacalogic Properties of Molecular Tweezers

Molecular tweezers (MTs) are compounds that act as Misfolded-Protein Clearance Enhancers (MPCEs) using a unique mechanism. They remodel the self-assembly of amyloidogenic proteins into formation of non-toxic and non-amyloidogenic structures that can be degraded efficiently by the natural clearance mechanisms. A lead MT called CLR01 has been found to prevent the self-assembly of multiple ...

June 25, 2015

Gal Bitan

IDENTIFIED: AN ELUSIVE TOXIN THAT DAMAGES NEURONS

With unfavorable conditions, the normally helpful astrocytes can become inflammatory and release a substance that is toxic to neurons. In a breakthrough discovery after years of searching, researchers have identified the toxic substance as saturated lipids. These toxins induced the death of nearby injured neurons and contributed to neurodegeneration in ...

October 7, 2022

Genes to Therapies: One Year Later

In just its first year of operation, Cure Alzheimer’s Fund’s ambitious new Genes to Therapies™ (G2T) research program has bloomed far beyond expectations. “We’re firing on all cylinders now,” says Research Consortium Chair Dr. Rudy Tanzi. “It’s exactly where we need to be headed to stop this disease.” In 2015, Cure Alzheimer’s ...

February 12, 2016

Laura Santambrogio

Dr. Laura Santambrogio received her Ph.D. from Padua University and trained as a post-doctoral fellow at NYU and Harvard Medical School with Jack Strominger.  She was recruited at Albert Einstein College of Medicine with an Irene Diamond Professorship in Immunology and recently moved to Weill Cornell where she held the position ...

April 14, 2021

Laura Santambrogio