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Diagnosing Alzheimerā€™s: New Blood Test Suggests Possible Breakthrough

A new blood test, which has the potential to accurately diagnose Alzheimerā€™s disease in individuals and significantly advance drug testing and research on the disease, has been developed through grant funding by Cure Alzheimer’s Fund.Ā  The test, known as Immunosignature (IS) and developed by a team led by UCLA neurologist Lucas ...

April 28, 2014

Rudy Tanzi Joins Francis Collins, Director of the National Institutes of Health, Eric Lander of the Broad Institute and Others to Explore Genetic Testing on NOVA

Last week, Cure Alzheimerā€™s Fund Research Consortium chairman Rudy Tanzi was featured on NOVA in a segment concerning genetic testing. The special followed several cases of people affected by genetic testing, showing both its benefits and challenges. NOVA only briefly touched on Alzheimerā€™s disease, but provided a comprehensive explanation of ...

April 4, 2012

Spinal Fluid Tests: Who Are They Really Good For?

A NYT article about the value of using spinal fluid tests to determine the presence of Alzheimerā€™s disease is optimistic and hopeful but maybe too much so. In an article published yesterday, Gina Kolata writes ā€œResearchers are finding simple and accurate ways to detect Alzheimerā€™s long before there are definite ...

August 11, 2010

Alzheimerā€™s Disease Genes: How Many Do We Know and What Can We Do With Them?

Rudolph E. Tanzi, Ph.D., Joseph P. and Rose F. Kennedy Professor of Neurology, Harvard Medical School; Director, Genetics and Aging Research Unit, Massachusetts General Hospital Ā  The four known Alzheimerā€™s genes. Over the past several decades, it has become increasingly clear that inheritance plays a major role in Alzheimerā€™s disease. The roughly 25,000 ...

July 14, 2011

SHOULD YOU FIND OUT IF YOUā€™RE AT RISK OF ALZHEIMERā€™S?

With a simple at-home genetics test, some people are learning they have a higher risk of Alzheimerā€™s. Can they do anything to prevent the disease? By Sumathi Reddy Updated July 15, 2019 9:14 am ET When Theresa Braymer canā€™t remember a word or name, she sometimes second-guesses herself. At 59, she is young to ...

October 6, 2019

How Can We Overcome Alzheimerā€™s?

Below is the text from an article included on the Eureka blog which provides an overview of the need for a multi-pronged approach to stopping Alzheimer’s disease. The work of Dr.’s Rudy Tanzi and David Holtzman, and the late Stephen Wagner, of the Cure Alzheimer’s Fund Research Leadership Group, is ...

November 2, 2023

Biochemical Mapping of the GSM Binding Site of Novel Pyridazine-Derived Small Molecule Gamma-Secretase Modulators

2019 Alzheimerā€™s disease is a huge health problem that imposes a severe social and economic burden; in the absence of an effective disease-modifying treatment, it is projected to become a dominant source of health care expenditures over the next several decades. Unfortunately, existing treatments are palliative, providing only temporary symptomatic benefit. ...

August 9, 2018

Steven L. Wagner, Yueming Li