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Happy Holidays!

During this holiday season, we would like to say thank you for everything you have done this year to help us in our search for a cure. As you know, our ability to fight this disease comes from each and every one of you! We are the only organization with a ...

December 22, 2009

Colby Davis of Boston

Colby Davis of Boston has selected Cure Alzheimer’s Fund as the beneficiary of its Pendants with a Purpose campaign in honor of Alzheimer’s Awareness Month in November. The ‘Pendants with a Purpose’ campaign launched in October 2023, to provide customers with an opportunity to purchase a specialized pendant each month to ...

November 8, 2023

Want to Sail on an America’s Cup Yacht?

Here is your chance. Cure Alzheimer’s Fund is proud to be taking part in Massachusetts General Hospital’s America’s Cup Experience on June 24, 2008. Cure Alzheimer’s Fund co-Founder, Phyllis Rappaport, will be captaining one of the boats and would like to invite you to join her as a crew member! She ...

August 20, 2009

Scaling Heights to Cure Alzheimer’s

Alan Arnette began this journey, his Road Back to Everest: Memories are Everything Campaign in June 2007 with a climb on Denali in Alaska. His adventures are more then just mountaineering excursions as this quest also involves trying to raise $100,000 for Alzheimer’s disease research. In September, he continued on to ...

January 1, 2008

Regulation of Tau Oligomerization by Interaction with TIA-­‐1, a Component of Stress Granules

Published work from multiple groups indicates that tau phosphorylation causes tau to mis-­‐localize to the soma and dendrites, where TIA-­‐1 is present [20][21][22]. Our preliminary   data   indicates   that   the   TIA-­‐1   binds   the phosphorylated tau. Tau promotes formation of TIA-­‐1 based SGs, and in the process, binding of Tau with TIA-­‐1 ...

July 17, 2014

Benjamin Wolozin

Eldercare Provider is Auspicious Neighbor

In May, Cure Alzheimer’s Fund moved its Massachusetts headquarters to a new location in Wellesley Hills. Our neighbor, CareScout, shares a passion for ending Alzheimer’s disease, and it has been a pleasure to get to know them and their business.     CareScout has been helping Americans chose an eldercare provider (home care, ...

October 9, 2007

Dr. Tanzi Featured Expert on Alzheimer’s Genome Project™ on Curiosity.com

Dr. Rudolph Tanzi, chairman of the Cure Alzheimer’s Fund Research Consortium, is now featured on the Discovery Channel-based website Curiosity.com. Tanzi provides answers to numerous questions posed by Curiosity with the intention of informing the public about Alzheimer’s disease and the Alzheimer’s Genome Project™. To see some of the answers to today’s most pressing ...

January 26, 2012

Elucidating Mechanisms Driving the Compromised Balance Between Mitophagy and cGAS-STING-Initiated Inflammation Towards a Treatment for Alzheimer’s Disease

There were over 55 million people living with dementia worldwide in 2020. This figure is projected to increase significantly, reaching 78 million in 2030 and 139 million in 2050. Alzheimer’s disease (AD) is the primary form of dementia, accounting for an estimated 60% to 80% of cases. In the brain ...

August 22, 2024

Evandro F. Fang, Per Nilsson

APP Gene Dose-Mediated Dysregulation of the Endolysosomal Network Acts to Compromise Synaptic Structure and Function Leading to Alzheimer’s Disease in Down Syndrome

Synapse loss is a critical manifestation of Alzheimer’s disease (AD) pathogenesis that results in progressive cognitive decline. Accordingly, interventions targeting synaptic changes may prevent or reverse cognitive decline and neurodegeneration. However, mechanisms that initiate synapse loss are poorly understood. People with Down syndrome (DS) are at increased risk of AD, ...

December 21, 2023

William C. Mobley