October 9, 2019
October 9, 2019
We are investigating the mechanisms that cause neurodegeneration in Alzheimer’s disease. Our recent studies have led us to realize that a toxic protein is unexpectedly secreted by a class of brain cells called astrocytes in the setting of Alzheimer’s disease. Our goal in this proposal is to identify this protein ...
September 28, 2015
January 30, 2024
Alzheimer’s disease was discovered over 110 years ago. Little was known about the disease and little more was learned. Our founders, frustrated by the slow pace of research into Alzheimer’s disease, decided to leverage their experience in venture capital and corporate start-ups and build a fund designed specifically to accelerate research, ...
September 24, 2017
A promising first-in-class drug stimulates the creation of new nerve cells in the brains of Alzheimer’s mice and will soon be tested in the brains of human patients, thanks to new research by Dr. Sam Gandy, member of Cure Alzheimer’s Fund’s Research Consortium, at Mount Sinai School of Medicine in ...
August 12, 2014
April 16, 2024
The specific hypothesis behind the proposed research is that presenilin 1 regulates cell fate determination of adult neural progenitor cells by interfering with instructive intercellular signals prevailing within the neural progenitor cell niche, and that expression of the familial AD-linked presenilin 1adversely affects this process.
February 11, 2011
January 30, 2024
December 6, 2018
April 24, 2019