Join us on Earth Day (4/22) 2016 to learn about air pollution and Alzheimer’s with Dr. Caleb Finch of University of Southern California. New evidence—funded by Cure Alzheimer’s Fund (CAF) and others—has emerged suggesting a strong connection between urban air pollution and Alzheimer’s disease. “These findings underscore the complexity of this ...
April 22, 2016
Join us for a great day of golf for a great cause! Cure Alzheimer’s Philadelphia is hosting a golf tournament at the beautiful and exclusive Bidermann Golf Course in Wilmington, DE on September 14. All proceeds from the event will go to Cure Alzheimer’s Fund for the support of Alzheimer’s ...
August 7, 2015
The core research effort currently funded by Cure Alzheimer’s Fund is the Alzheimer’s Genome Project™ initiative. This project, entirely funded by Cure Alzheimer’s Fund, is being led by Dr. Rudolph Tanzi at Massachusetts General Hospital. The objective is to identify all genes that contribute significant risk for Alzheimer’s disease, thereby ...
August 20, 2009
From an article in Medical News Today about a paper recently released in the journal Neuron, June 7, 2007: Researchers from the MassGeneral Institute for Neurodegenerative Disorders (MGH-MIND) have discovered how brain cells affected by stroke or head injury may cause generation of amyloid-beta protein, which is a key factor in ...
August 20, 2009
December 14, 2021
This past June, 60 players and guests gathered at Raven’s Claw Golf Club in Pottstown, Pennsylvania, for the annual Bryn Mawr Rotary Club golf outing; Cure Alzheimer’s Fund and two other organizations benefited from their day. Jeff Morby, co-founder of Cure Alzheimer’s Fund and a Rotary member, spoke last June ...
October 16, 2015
Indications of Alzheimer’s disease
September 24, 2017
As a result of an Ames positive result in a single salmonella strain (T98), the FDA is requiring that, prior to our pre-IND meeting with them, we perform a GLP Ames assay with a form of BPN-15606 (besylate salt form) that is equivalent to what will be used in our ...
April 26, 2016
This project focuses on ultimately defining the structure of a soluble gamma-secretase modulator (SGSM)-bound gamma-secretase enzyme complex at high resolution. Defining the structure of this complex will provide critical information towards elucidating the mechanism of action of this promising series of therapeutic molecules known as SGSMs. This structural information will enable molecular dynamics simulations ...
July 10, 2013
The immune system uses complement proteins and receptors to “coat and clear” pathogens and proteins from the body. Complement Receptor 1 (CR1/CD35) is found on the surface of red blood cells in humans and helps shuttle cellular debris to the liver for degradation. Recently, specific genetic variations, called polymorphisms, in ...
September 28, 2015
