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DIGITAL ART AUCTION TO BENEFIT OUR RESEARCH

From October 23 through October 27, leading generative art platform Art Blocks will be hosting an exclusive auction of works by five leading artists worldwide. With every day of the week designated to a different artist, the auction sets out to unite artists and collectors in the fight against neurodegenerative ...

October 7, 2023

Antibody Signature of Alzheimerā€™s Disease: Promise of an Early Diagnostic Test

A physician canā€™t cure what he canā€™t diagnose. The diagnosis of Alzheimer’s disease is based on the exclusion of several neurological syndromes, rather than directly testing for the disease of interest. This can be an inaccurate exercise in up to 20% of the cases. Promising biomarkers are being developed, such ...

January 31, 2013

Lucas Restrepo

TREM2 ANTIBODIES REDUCE AD PATHOLOGY

Microglia are the innate immune cells that reside in the central nervous system and remove unwanted particles and debris from the brain. TREM2 is a receptor found on microglia and its activation increases amyloid beta uptake; the effect is therefore neuroprotective. An antibody designed to increase TREM2 activation has shown ...

October 7, 2022

Deficits in the Blood-Brain Barrier Play a Role in Alzheimer’s Disease Pathology: A New 3D Tissue Model Provides a Potential Target for Developing Therapy

A new Alzheimer’s disease (AD) model suggests that defects in the blood-brain barrier (BBB) play a key role in worsening amyloid plaques and neurofibrillary tangles, and that therapies to reduce gaps in the BBB hold promise for treatment of the disease. The new model uses ā€œmicrofluidicsā€ to examine how a layer ...

October 9, 2019

Leveraging Cure Alzheimerā€™s Fund support leads to impressive RO1 grants

At Cure Alzheimerā€™s Fund, one of our successful strategies is to fund research that is innovative and based on high-quality science yet deemed risky by traditional funding sources. Our entrepreneurial approach and ability to provide funds in a quick and efficient manner allows us to fund potentially groundbreaking work that ...

December 15, 2010

The New York Times Asks: “Will We Ever Cure Alzheimerā€™s?”

To mark the 40th anniversary of the Science section of The New York Times, the editors made a list of their 11 most pressing science questions they would like answered in the coming years. Given the scale of Alzheimerā€™s diagnosis in the United States, it is no surprise that the ...

December 13, 2018

Alzheimerā€™s Genes in the News: What does it all mean?

Setting the stage The 10th Annual International Conference on Alzheimerā€™s Disease/Parkinsonā€™s Disease (AD/PD) was held this March in Barcelona with thousands of researchers from 68 countries attending. Chief among the topics of interest was determining risk for the disease from genetics. The useful source for all things Alzheimerā€™s, The Alzheimerā€™s Research ...

April 7, 2011