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Targretin Fails: High Hopes Dashed for a New Treatment for Alzheimer’s

While many were anxious to accept initial findings showing a drug known as Targretin’s “too good to be true” lab results with Alzheimer’s disease, subsequent attempts to confirm and replicate the original data regarding the ability of Targretin to remove amyloid plaques, the cardinal lesion of the disease, have largely ...

May 24, 2013

The Basics of Drug Discovery

The path from research discovery to drug development can be a long one. Current estimates target the time for an Alzheimer’s drug to get to market at around 12 years. However, with new technological advances in such areas as genetics, we are optimistic that scientific opportunities have never been greater to ...

August 20, 2009

LOVE DEEPLY WEEP FREELY

Lisa Husted founded her company to provide comfort to those whose hearts are full of emotion and to grant them permission to cry in happy times and difficult times. The original design of the REMEMBRANCE handkerchief depicts two grey doves nestled among forget-me-nots, amidst a background of tiny blue dots. ...

October 30, 2020

Donate

Contact us about supporting Cure Alzheimer’s Fund at: Email: [email protected] Cure Alzheimer’s Fund is a “doing business as” name for the Alzheimer’s Disease Research Foundation, a 501(c)(3) public charity with federal tax ID #52-239-6428. Please note that your information will be used only by Cure Alzheimer’s Fund to record and acknowledge this ...

September 24, 2017

Stem Cell Model of Familial Alzheimer’s Identifies New AD Genes

A stem cell model of familial Alzheimer’s disease (FAD) was successfully generated in a recent study, allowing researchers to identify 14 genes potentially implicated in the disease. One gene in particular demonstrates the important role inflammation may play in the brain of Alzheimer’s patients. The study was completed by scientists ...

January 8, 2014

APOE and Alzheimer’s Disease

Co-chaired by three members of CAF’s Research Consortium—Drs. David Holtzman, Sam Sisodia and Rudy Tanzi—participants included all the other members of the Research Consortium (except Virginia Lee, who had a prior commitment) and several invited guests whose records of research include valuable insights into this relationship. The guests were Michael ...

April 21, 2010