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John Sondek

John Sondek, Ph.D. is Professor of Pharmacology and Biochemistry & Biophysics, member of the Lineberger Comprehensive Cancer Center, and Director of the UNC Center for Structural Biology. Dr. Sondek has published over 100 scientific articles and is co-inventor on 6 patents. In recognition of his research, he has received awards ...

December 21, 2020

John Sondek

Pre-Clinical Testing of CDK4/6 Inhibitors as a Therapeutic Strategy in Alzheimer’s Disease Using Alzheimer’s Disease Tauopathy Mouse Model

We recently found that a class of clinically approved anti-cancer compounds reversed memory loss and restored normal numbers of synapses and dendritic spines in mouse models of Alzheimer’s Disease (AD). These findings offer an exciting possibility these compounds could be used to reverse the symptoms of AD in AD patients. ...

September 24, 2024

Peter Sicinski

Continued Growth Puts Focus on Research

With 10 years of research behind us, Cure Alzheimer’s Fund continues to grow, with the quality of our research remaining extraordinary. To build on our success, we recently welcomed four new Research Consortium members and four new employees to our organization. Christoph Lange, Ph.D., Harvard T.H. Chan School of Public Health, ...

July 22, 2015

Allyn C. Woodward Jr.

It is with heavy hearts that we announce the passing of Allyn C. Woodward Jr, a beloved husband, father, grandfather, and friend of many on Thursday, August 17, 2023. Allyn was a loving father and devoted family man. He leaves behind a lasting legacy of values, traditions, and memories that will ...

August 21, 2023

Charles P. Waite

Charles Prescott Waite passed away peacefully at his home in San Francisco on June 4, 2019. Born on March 30, 1930, in Manchester, CT, he attended Manchester High School graduating in 1947. Charlie ran the mile on the state champion track team as well as cross country. He married Catherine ...

June 10, 2019

Beverly L. Davidson

Dr. Davidson received her Ph.D. in biological chemistry from the University of Michigan and in 1994 was recruited to the University of Iowa, where she was promoted to associate professor in 1999 and professor in 2001. From 1999–2014 she held the Roy J. Carver Chair in Biomedical Research, and was ...

December 24, 2017

Small Molecule Activators of PLC-gamma-2 as Novel Therapeutics for Alzheimer’s Disease

Current drugs used to treat Alzheimer’s disease (AD) ameliorate the symptoms of the disease but do not slow or reverse disease progression. Part of the reason for this has been a lack of knowledge on specific and actionable biological molecules that contribute to the disease and that can be targeted ...

December 21, 2020

John Sondek, Kenneth Pearce, Qisheng Zhang

Eric Schadt

Dr. Schadt is Director of the Icahn Institute for Genomics and Multiscale Biology, Chair of the Department of Genetics and Genomics Sciences, and the Jean C. and James W. Crystal Professor of Genomics at the Icahn School of Medicine at Mount Sinai. Dr. Schadt is an expert on the generation and integration ...

August 28, 2016

Neuronal Mechanisms Driving Synapse Loss in Alzheimer’s Disease

In Alzheimer’s disease (AD), one of the biggest reasons people experience memory and thinking problems is because the connections between brain cells (synapses) get weaker and disappear. Previous research suggests that immune cells and support cells in the brain are responsible for this loss. One reason these cells might be ...

January 10, 2024

Martin Kampmann

Katherine Schwetye

Dr. Kate Schwetye earned a combined M.D.-Ph.D. from Washington University School of Medicine in St. Louis (WUSTL), where she worked in the labs of Drs. David Holtzman and David Brody studying the dynamics of amyloid-beta peptide in vivo in the brain interstitial fluid in a mouse model of traumatic injury ...

February 23, 2023

Katherine Schwetye