Lucas Restrepo, M.D., Ph.D.

Clinical Assistant Professor of Neurology
Department of Neurology,
David Geffen School of Medicine
University of California, Los Angeles

Lucas Restrepo obtained his MD degree from the Health Science Institute in Columbia, South America in 1993, completing his neurology residency at Georgetown University in 2000 and a stroke fellowship at Johns Hopkins Hospital with Robert J. Wityk in 2002. He has earned several academic awards, including “intern of the year” at the University of Texas Health Science Center in San Antonio in 1996 and being named “neurology attending of the year” by the UCLA neurology residents in 2006 and 2010. He earned a PhD in Molecular and Cell Biology at Arizona State University in 2011 under the mentoring of Stephen Albert Johnston. Dr Restrepo has published over 40 papers in peer-reviewed journals, some with relevant impact. Two of his papers about advanced MRI techniques and transcranial Doppler ultrasound for the evaluation of the pathophysiology of brain ischemia were selected as “best paper (s) published in the Journal of Neuroimaging” for 2 consecutive years (2003 and 2004). He is currently a Clinical Assistant Professor of Neurology at the David Geffen School of Medicine at UCLA. 

Funded Research

Project Description Researchers Funding
Antibody Signature of Alzheimer’s Disease: Promise of an Early Diagnostic Test

A physician can’t cure what he can’t diagnose. The diagnosis of Alzheimer's disease is based on the exclusion of several neurological syndromes, rather than directly testing for the disease of interest. This can be an inaccurate exercise in up to 20% of the cases. Promising biomarkers are being developed, such as the cerebrospinal fluid profile of beta amyloid and tau proteins, as well as amyloid imaging with positron-emission tomography.


Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.
(S38.002) Lucas Restrepo, Phillip Stafford and Stephen Johnston, High Accuracy of a Microarray-Based Blood Test for Alzheimer’s Disease (S38.002), Neurology, 82(10), April 8, 2014