Since our inception in 2004, our steadfast focus has been providing research grants to the worlds’ leading scientists researching Alzheimer’s disease. We are honored to work with scientists who are passionate in their pursuit to rid our world of this debilitating disease.

Many of the funded projects have resulted in significant breakthroughs in developing a better understanding of Alzheimer’s disease and getting closer to a cure.

Randall Bateman | 2017

Stable Isotope Labeling and Quantitative Mass Spectrometry Imaging of Alzheimer’s Disease Pathology in Human Brain

Benjamin Wolozin | 2017

Inhibition of Tau Pathology in Human Neurons

David Holtzman | 2017

Understanding the Effect of APOE on Tau-Mediated Neurodegeneration

Guojun Bu | 2017

Effects of Peripheral APOE on Central Nervous System Functions and AD Pathogenesis

Oleg Butovsky | 2017

The Role of APOE in Microglia Regulation in Neurodegeneration

Cheryl Wellington | 2017

Using Human Bioengineered Cerebral Vessels to Explore How Native APOE Affects Cerebrovascular Properties Relevant to Alzheimer’s Disease

Randall Bateman | 2017

APOE Proteoforms in Human CNS and Validation of APOE Pharmacodynamic Translational Markers

Paul Greengard | 2017

Impact of APOE and Sex on Vulnerable Neuron-Specific Functional Network

Karen Duff, Natura Myeku | 2017

Propagation of Tauopathy and Ubiquitin Proteasome System Dysfunction: Impact and Rescue with a UPS Activator

| 2017

Role of ATXN1 in Regulating BACE1 Activity

Winston Hide | 2016

CIRCUITS: Utilizing Functional Maps to Prioritize Therapeutic Targets in Alzheimer’s Disease

Joseph Ecker, Rudolf Jaenisch | 2016

CIRCUITS: Whole Genome Characterization of DNA Methylation Changes in the Aged and Alzheimer’s Disease Human Brain

Funded Projects

The science that has advanced our understanding of Alzheimer's disease