Cure Alzheimer’s Fund created the first 8 Areas of Focus in order to better define our goals and focus research dollars where they are most likely to find a cure as fast as possible. However, we remain open to supporting rigorous investigations of intriguing ideas and theories outside these categories-from unexpected sources or disciplines or the emergence of new knowledge-when our Research Leadership Group and Scientific Advisory Board believe compelling scientific data justifies doing so. The Individual Projects category is designed to accommodate any project we choose to fund outside our core areas; some will prove to be so important that they justify the establishment of a new area. Neuroscience, epigenetics, proteomics, machine learning: Alzheimer’s disease research involves some of the most dynamic and least-conquered areas of science, and we are committed to remaining flexible and responsive as we pursue a cure.