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2025-06-23
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2025-06-23
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2025-06-22
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2025-06-20
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2025-06-20
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2025-06-19
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2025-06-18
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2025-06-18
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2025-06-16
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2025-06-16
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2025-06-12
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2025-06-12
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2025-06-09
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2025-06-09
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2025-06-09
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Current Methods in Clinical Alzheimer’s Disease Research and Diagnosis, Molecular Diagnosis & Therapy |
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2025-06-07
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2025-06-07
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Brain-derived tau to measure treatment effect in Alzheimer’s disease and frontotemporal dementia, Alzheimer's & Dementia |
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2025-06-05
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LC-MS/MS proteomics identifies plasma proteins related to cognition over 9-year follow-up, Alzheimer's & Dementia |
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2025-06-05
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2025-06-04
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2025-06-03
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2025-06-02
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2025-06-02
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Chronic Intraventricular Cannulation for the Study of Glymphatic Transport, eNeuro |
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2025-06-02
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2025-05-30
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Rapid and high-yield recovery of plasma-derived extracellular vesicles using modified chromatography with soluble protein depletion for biomarker discovery, Cell Communication and Signaling |
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2025-05-30
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Proteomic signatures of corona and herpes viral antibodies identify IGDCC4 as a mediator of neurodegeneration, Science Advances |
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2025-05-30
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2025-05-29
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Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference, Alzheimer's & Dementia |
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2025-05-29
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Testing Protein Stress Signals in Peripheral Immunocytes Under the Same Treatment Capable of Decreasing the Incidence of Alzheimer’s Disease in Bladder Cancer Patients, Current Issues in Molecular Biology |
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2025-05-26
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Neurofilament light chain as a biomarker for neuronal injury in CNS infections, Expert Review of Molecular Diagnostics |
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2025-05-25
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Tailoring thresholds for interpreting plasma p-tau217 levels, Journal of Neurology, Neurosurgery, and Psychiatry |
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2025-05-24
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2025-05-23
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2025-05-23
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2025-04-22
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2025-04-10
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2025-04-09
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2025-03-25
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2025-03-23
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Data-driven evaluation of suitable immunogens for improved antibody selection, Protein Science |
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2025-03-20
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2025-03-17
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2025-03-10
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2025-03-10
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2025-03-08
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2025-03-06
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2025-02-26
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2025-02-26
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A head-to-head comparison of plasma biomarkers to detect Alzheimer’s disease in a memory clinic, Alzheimer's & Dementia |
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2025-02-25
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2025-02-25
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2025-02-23
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Machine learning prediction of tau-PET in Alzheimer’s disease using plasma, MRI, and clinical data, Alzheimer's & Dementia |
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2025-02-22
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2025-02-22
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2025-02-21
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Mechanisms of astrocyte aging in reactivity and disease, Molecular Neurodegeneration |
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2025-02-21
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2025-02-21
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Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates, Cell Reports |
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2025-02-20
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2025-02-19
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The impact of kidney function on Alzheimer’s disease blood biomarkers: implications for predicting amyloid-β positivity, Alzheimer's Research & Therapy |
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2025-02-19
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2025-02-18
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Temporal Dynamics and Biological Variability of Alzheimer Biomarkers, JAMA Neurology |
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2025-02-17
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2025-02-17
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Validation of a novel neuroimaging signature for dementia and clinical Alzheimer’s disease in the population-based Rotterdam study, Journal of Alzheimer's Disease |
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2025-02-16
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2025-02-15
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Plasma Hepcidin as a potential informative biomarker of Alzheimer disease and vascular dementia, Alzheimer's Research & Therapy |
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2025-02-13
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The neuroimmune connectome in health and disease, Nature Medicine |
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2025-02-12
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Predicting survival rate by plasma biomarkers and clinical variables in syndromes associated with frontotemporal lobar degeneration, Alzheimer's & Dementia |
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2025-02-12
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Soluble cerebral Aβ protofibrils link Aβ plaque pathology to changes in CSF Aβ42/Aβ40 ratios, neurofilament light and tau in Alzheimer’s disease model mice, Nature Aging |
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2025-02-12
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Repurposing peripheral immunocytesof Bacillus Calmette Guerin-vaccinated melanoma patients to reveal preventive Alzheimer’s disease mechanisms, possibly via the unfolded protein response, Journal of Alzheimer's Disease Reports |
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2025-02-10
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2025-02-10
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Blood biomarkers to identify patients with different intracranial lesion combinations after traumatic brain injury, Brain and Spine |
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2025-02-08
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2025-02-06
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Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypes, Science Translational Medicine |
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2025-02-05
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Regional brain structural alterations in reward and salience networks in asthma, Brain, Behavior, and Immunity |
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2025-02-05
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Differential roles of Alzheimer’s disease plasma biomarkers in stepwise biomarker-guided diagnostics, Alzheimer's & Dementia |
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2025-02-05
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Microglial cGAS Deletion Preserves Intercellular Communication and Alleviates Amyloid-β-Induced Pathogenesis of Alzheimer’s Disease, Advanced Science |
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2025-02-05
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The Alzheimer’s Association Global Biomarker Standardization Consortium (GBSC) plasma phospho-tau Round Robin study, Alzheimer's & Dementia |
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2025-02-05
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Iron chelation by oral deferoxamine treatment decreased brain iron and iron signaling proteins, Journal of Alzheimer's Disease |
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2025-02-02
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Identification and development of cGAS inhibitors and their uses to treat Alzheimer’s disease, NeuroTherapeutics |
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2025-01-31
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Inflammation biomarkers and Alzheimer’s disease: A pilot study using NULISAseq, Alzheimer's & Dementia |
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2025-01-30
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MRI-guided clustering of patients with mild dementia due to Alzheimer’s disease using self-organizing maps, NeuroImage Reports |
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2025-01-30
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Toward a biological definition of neuronal and glial synucleinopathies, Nature Medicine |
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2025-01-30
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Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection, Nature Medicine |
Duff, E. P., Zetterberg, H., Heslegrave, A., Dehghan, A., Elliott, P., Allen, N., Runz, H., Laban, R., Veleva, E., Whelan, C. D., Sun, B. B., & Matthews, P. M. |
2025-01-30
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Iron-associated lipid peroxidation in Alzheimer’s disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice, Alzheimer's & Dementia |
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2025-01-29
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The value of CSF diagnostic and prognostic biomarkers in NMOSD and MOGAD in real-life use, Multiple Sclerosis and Related Disorders |
Johnsson, M., Eriksson, K., Rosenstein, I., Novakova, L., Malmeström, C., Lycke, J., Sandgren, S., Zetterberg, H., Blennow, K., Johansson, K., & Axelsson, M. |
2025-01-29
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The meninges host a distinct compartment of regulatory T cells that preserves brain homeostasis, Science Immunology |
Marin-Rodero, M., Cintado, E., Walker, A. J., Jayewickreme, T., Pinho-Ribeiro, F. A., Richardson, Q., Jackson, R., Chiu, I. M., Benoist, C., Stevens, B., Trejo, J. L., & Mathis, D. |
2025-01-28
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Lipidome disruption in Alzheimer’s disease brain: detection, pathological mechanisms, and therapeutic implications, Molecular Neurodegeneration |
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2025-01-27
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Alzheimer’s disease risk ABCA7 p.A696S variant disturbs the microglial response to amyloid pathology in mice, Neurobiology of Disease |
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2025-01-27
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Polygenic risk discriminates Lewy body dementia from Alzheimer’s disease, Alzheimer's & Dementia |
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2025-01-24
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Cerebral Microbleeds and Amyloid Pathology Estimates From the Amyloid Biomarker Study, JAMA Network Open |
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2025-01-22
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The Impact of Optical Undersampling on the Ca2+ Signal Resolution in Ca2+ Imaging of Spontaneous Neuronal Activity, Journal of Integrative Neuroscience |
Milicevic, K. D., Ivanova, V. O., Brazil, T. N., Varillas, C. A., Zhu, Y. M. D., Andjus, P. R., & Antic, S. D. |
2025-01-21
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Short-term variability of Alzheimer’s disease plasma biomarkers in a mixed memory clinic cohort, Alzheimer's Research & Therapy |
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2025-01-21
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Novel synaptic markers predict early tau pathology and cognitive deficit in an asymptomatic population at risk of Alzheimer’s disease, Molecular Psychiatry |
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2025-01-18
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Plasma biomarkers of amyloid, tau, astrogliosis, and axonal injury in a mixed memory clinic cohort, Alzheimer's & Dementia |
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2025-01-16
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2025-01-16
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Know your brain aging to know your resilience in neurodegenerative diseases, Brain Communications |
Ng, B., & Zetterberg, H. |
2025-01-15
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Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy, Science Translational Medicine |
Brandao, W., Jain, N., Yin, Z., Kleemann, K. L., … Ulrich, J. D., Blurton-Jones, M., Ilin, I., Weiner., H. L., Holtzman, D. M., Butovsky, O. |
2025-01-15
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NR1D1 Inhibition Enhances Autophagy and Mitophagy in Alzheimer’s Disease Models, Aging and Disease |
Zhang, S. Q., Niu, Z., Anisimov, A., Shi, F., Deng, S., Xiao, X., Cao, S. Q., Pan, J. P., Wang, H. L., Lagartos-Donate, M. J., Bozbas, N. G., Wang, P. J., Ai, R., Li, Y., Yang, G., Lautrup, S., & Fang, E. F. |
2025-01-14
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Myelin debris as an initiator of microglial dysfunction and neuropathology in Alzheimer’s disease, Cellular & Molecular Immunology |
Samuels, J. D., & Lukens, J. R. |
2025-01-14
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2023-02-15
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2023-02-07
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2020-07-01
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2020-06-30
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2020-06-24
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2020-06-24
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2020-06-23
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2020-06-16
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2020-06-10
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2020-06-09
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2020-06-01
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2020-05-29
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2020-05-20
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2020-05-19
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2020-05-18
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2020-05-15
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2020-04-29
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2020-04-17
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2020-04-17
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2020-04-13
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2020-04-06
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The Alzheimer Disease-Causing Presenilin-1 L435F Mutation Causes Increased Production of Soluble Aβ43 Species in Patient-Derived iPSC-Neurons, Closely Mimicking Matched Patient Brain Tissue, Journal of Neuropathology & Experimental Neurology |
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2020-04-04
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2020-04-02
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2020-03-27
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An Ocular Glymphatic Clearance System Removes β-Amyloid From the Rodent Eye, Science Translational Medicine |
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2020-03-25
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2020-03-25
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Identification of Novel Alzheimer’s Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data, Scientific Reports |
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2020-03-19
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2020-03-13
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2020-03-13
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Increased plasma bradykinin level is associated with cognitive impairment in Alzheimer’s patients, Neurobiology of Disease |
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2020-03-12
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2020-03-11
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Implicating endothelial cell senescence to dysfunction in the ageing and diseased brain, Basic & Clinical Pharmacology & Toxicology |
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2020-03-11
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2020-03-10
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2020-03-09
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2020-03-09
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2020-03-06
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2020-03-03
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Safety and pharmacological characterization of the molecular tweezer CLR01- a broad spectrum inhibitor of amyloid protein’s toxicity, BMC Pharmacology and Toxicology |
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Amyloid-beta and Tau: the trigger and bullet in Alzheimer’s disease pathogenesis, JAMA Neurology |
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2014-04-01
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Assessment of micro-RNA-related SNP effects in the 3′ untranslated region of the IL22RA2 risk locus in multiple sclerosis, Neurogenetics |
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2014-03-18
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Targeting the beta secretase BACE1 for Alzheimer’s disease therapy, Lancet Neurology |
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2014-02-03
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Different effects of anesthetic isoflurane on caspase-3 activation and cytosol cytochorne mice levels between m neural progenitor cells and neurons, Frontiers in Cellular Neuroscience |
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2014-01-22
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Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice, Scientific Reports |
Xu, Z., Dong, Y., Wang, H., Culley, D. J., Marcantonio, E. R., Crosby, G., Tanzi, R. E., Zhang, Y., & Xie, Z. |
2014-01-20
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Characterization and molecular profiling of PSEN1 familial Alzheimer’s disease iPSC-derived neural progenitors, PLoS One |
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2014-01-08
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Generation of iPSC lines from archived non-cryoprotected biobanked dura mater, Acta Neuropathologica Communications |
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2014-01-07
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Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase, Molecular Neurodegeneration |
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2014-01-04
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A function for EHD family proteins in unidirectional retrograde dendritic transprt of BACE1 and Alzheimer’s disease Ab production, Cell Reports |
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2013-12-26
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A paired RNAi and RabGAP Overexpression screen identifies Rab11 as a regulator of beta-amyloid production, Cell Reports |
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2013-12-26
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Modulators of amyloid protein aggregation and toxicity: EGCG and CLR01, Translational Neuroscience |
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2013-12-20
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Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration, Journal of Clinical Investigation |
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2013-12-02
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Alzheimer’s disease: new data highlights nonneuronal cell types and the necessity for presymptomatic prevention strategies., Biological Psychiatry |
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2013-11-28
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A shortened Barnes Maze Protocol reveals memory deficits at 4-months of age in the triple-transgenic mouse model of Alzheimer’s disease, PLoS One |
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2013-11-13
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Exosomes neutralize synaptic-plasticity-disrupting activity of A beta assemblies in vivo, Molecular Brain |
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2013-11-13
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Surgical incision-induced nociception causes cognitive impairment and reduction in synaptic NMDA recptor 2B in mice, Journal of Neuroscience |
Zhang, X., Xin, X., Dong, Y., Zhang, Y., Yu, B., Mao, J., & Xie, Z. |
2013-11-06
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Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation, and survival of adult hippocampal progenitors., Molecular Neurodegeneration |
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2013-10-20
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Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition, and biomarkers, Brain Imaging and Behavior |
Shen, L., Thompson, P. M., Potkin, S. G., Bertram, L., Farrer, L. A., Foroud, T. M., Green, R. C., … Alzheimer’s Disease Neuroimaging Initiative |
2013-10-05
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ADAM10 Missense Mutations Potentiate beta-amyloid accumulation by impairing pro-domain chaperone function, Neuron |
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2013-09-19
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Neuroserpin up-regulation in the Alzheimer’s disease brain is associated with elevated throid hormone receptor-beta 1 and HuD expression, Neurochemistry International |
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2013-09-11
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Cancer prognosis: can anesthesia play a role?, Anesthesiology |
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2013-09-01
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Intra-hippocampal transplantation of neural precursor cells with transgenic over-expression of IL-1 receptor antagonist rescues memory and neurogenesis impairments in an Alzheimer’s disease model, Neuropsychopharmacology |
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2013-08-19
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Anaesthetic Neurotoxicity and Neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar, British Journal of Anaesthesia |
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2013-08-01
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Systematic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing A deposition and tau pathology in 3xTg AD mice, Journal of Neurochemistry |
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2013-08-01
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Cerebrospinal fluid Abeta to Tau ratio and postoperative cognitive change, Annals of Surgery |
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2013-08-01
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Molecular Mechanism of cognitive dysfunction following traumatic brain injury, Frontiers in Aging Neuroscience |
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2013-07-09
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Palmitoylation of Amyloid Precursor Protein regulates amyloidogenic processing in lipid rafts, Journal of Neuroscience |
Bhattacharyya, R., Barren, C., & Kovacs, D. M. |
2013-07-03
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Effects of Anesthetic Isoflurane and Desflurane on Human Cerebrospinal Fluid Aβ and τ Level, Anesthesiology |
Zhang, B., Tian, M., Zheng, H., Zhen, Y., Yue, Y., Li, T., Li, S., Marcantonio, E. R., & Xie, Z. |
2013-07-01
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Rare autosomal copy number variations in early-onset familial Alzheimer’s disease, Molecular Psychiatry |
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2013-06-11
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Serum iron levels and the risk of Parkinson Disease: A mendelian randomization study., PLoS Medicine |
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2013-06-04
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MANBA, CXCR5, SOX8, RPS6KB1, ZBTB46 are genetic risk loci for multiple sclerosis, Brain |
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2013-06-04
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Tranilast binds to A beta monomers and promotes A beta fibrillation, Biochemistry |
Connors, C. R., Rosenman, D. J., Lopes, D. H., Mittal, S., Bitan, G., Sorci, M., Belfort, G., Garcia, A., & Wang, C. |
2013-05-31
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Alzheimer’s disease risk gene CD33 inhibits microglial uptake of amyloid beta, Neuron |
Griciuc, A., Serrano-Pozo, A., Parrado, A. R., Lesinski, A. N., Asselin, C. N., Mullin, K., Hooli, B., Choi, S. H., Hyman, B. T., & Tanzi, R. E. |
2013-05-22
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Silencing of the Drosophila ortholog of SOX5 in heart leads to cardiac dysfunction as detected by optical coherence tomography, Human Molecular Genetics |
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2013-05-21
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Mutant presenilin 1 expression in excitatory neurons impairs enrichment-mediated phenotypes of adult hippocampal progenitor cells., Proceedings of the National Academy of Sciences of the United States of America |
Veeraraghavalu, K., & Sisodia, S. S. |
2013-05-14
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Ubiquilin-1 modulates gamma-secretase-mediated epsilon-site cleavage in neuronal cells, Biochemsitry |
Viswanathan, J., Haapasalo, A., Kurkinen, K. M., Natunen, T., Mäkinen, P., Bertram, L., Soininen, H., Tanzi, R. E., & Hiltunen, M. |
2013-05-10
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Isoflurane facilitates synaptic NMDA receptor endocytosis in mice primary neurons, Current Molecular Medicine |
Dong, Y., Wu, X., Zhang, G., Xu, Z., Zhang, Y., Gautam, V., Kovacs, D. M., Wu, A., Yue, Y., & Xie, Z. |
2013-05-01
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Isoflurane and sevoflurane increase interleukin-6 levels through the nuclear factor-kappa B pathway in neuroglioma cells, British Journal of Anaesthesia |
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2013-04-19
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In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis, Molecular Neurodegeneration |
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2013-04-19
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Protein sorting motifs in the cytoplasmic tail of SorCS1 control generation of Alzhiemer’s amyloid beta peptide, Journal of Neuroscience |
Lane, R. F., Steele, J. W., Cai, D., Ehrlich, M. E., Attie, A. D., & Gandy, S. |
2013-04-17
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Fine mapping of the amyloid β-protein binding site on myelin basic protein, Biochemistry |
Kotarba, A. E., Aucoin, D., Hoos, M. D., Smith, S. O., & Van Nostrand, W. E. |
2013-04-04
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Acute and traumatic encephalopathies: pathogenesis and biomarkers, Nature Reviews Neurology |
DeKosky, S. T., Blennow, K., Ikonomovic, M. D., & Gandy, S. |
2013-04-01
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Positron Emission Tomography Imaging of Fibrillar Parenchymal and Vascular Amyloid-beta in TgCRND8 Mice, ACS Chemical Neuroscience |
McLean, D., Cooke, M. J., Albay, R., 3rd, Glabe, C., & Shoichet, M. S. |
2013-03-19
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BACE1 and presenilin/gamma-secretase regulate proteolytic processing of KCNE1 and 2, auxilary subunits of voltage-gated potassium channels, The FASEB Journal |
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2013-03-15
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Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment, Anesthesiology |
Shen, X., Dong, Y., Xu, Z., Wang, H., Miao, C., Soriano, S. G., Sun, D., Baxter, M. G., Zhang, Y., & Xie, Z. |
2013-03-01
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Sevoflurane anesthesia in pregnant mice induces neurotoxicity in fetal and offspring mice, Anesthesiology |
Zheng, H., Dong, Y., Xu, Z., Crosby, G., Culley, D. J., Zhang, Y., & Xie, Z. |
2013-03-01
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Distinguishing true from false positives in genomic studies: p values, European Journal of Epidemiology |
Broer, L., Lill, C. M., Schuur, M., Amin, N., Roehr, J. T., Bertram, L., Ioannidis, J. P., & van Duijn, C. M. |
2013-02-01
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Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzhiemer’s like tauopathy, Journal of Neuroscience |
Iba, M., Guo, J. L., McBride, J. D., Zhang, B., Trojanowski, J. Q., & Lee, V. M. |
2013-01-16
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Genome-wide significant associations of ANKRD55 rs6859219 and multiple sclerosis risk, Journal of Medical Genetics |
Lill, C. M., Schjeide, B. M., Graetz, C., Liu, T., Damotte, V., Akkad, D. A., Blaschke, P., Gerdes, L. A., Kroner, A., Luessi, F., Cournu-Rebeix, I., Hoffjan, S., Winkelmann, A., Touze, E., Pico, F., Corcia, P., Otaegui, D., Antigüedad, A., Alcina, A., Comabella, M., … Bertram, L. |
2013-01-12
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Amyloid beta oligomerization in Alzheimer’s dementia versus high pathology controls, Annals of Neurology |
Esparza, T. J., Zhao, H., Cirrito, J. R., Cairns, N. J., Bateman, R. J., Holtzman, D. M., & Brody, D. L. |
2013-01-01
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Neurotoxicity of General Anesthetics: an update, Current Pharmaceutical Design |
Vlisides, P., & Xie, Z. |
2012-12-01
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Sleep disturbance induces neuroinflammation and impariment of learning and memory, Neurobiology of Disease |
Zhu, B., Dong, Y., Xu, Z., Gompf, H. S., Ward, S. A., Xue, Z., Miao, C., Zhang, Y., Chamberlin, N. L., & Xie, Z. |
2012-12-01
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Origins of Alzheiemr’s disease: reconciling cerebrospinal fluid biomarker and neuropathology data regarding the temporal sequence of amyloid beta and tau involvement, Current Opinion in Neurology |
Musiek, E. S., & Holtzman, D. M. |
2012-12-01
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Protection of primary neurons and mouse brain from Alzheimer’s pathology by molecular tweezers, Brain |
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2012-11-24
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Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of A beta amyloidosis, Journal of Experimental Medicine |
Kim, J., Eltorai, A. E., Jiang, H., Liao, F., Verghese, P. B., Kim, J., Stewart, F. R., Basak, J. M., & Holtzman, D. M. |
2012-11-19
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Independent replication of STAT3 association with multiple sclerosis risk in a large German case-control sample, Neurogenetics |
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2012-11-18
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Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast, Journal of Alzheimer's Disease |
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2012-11-14
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Reduction of synaptojanin1 ameliorates synaptic and behaviorla impariments in a mouse model of Alzheimer’s disease, Journal of Neuroscience |
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2012-10-31
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Intravenous delivery of targeted liposomes to amyloid-beta in APP/PSEN1 transgenic mice, PLoS One |
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2012-10-31
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Vps10 family proteins and the retromer complex in aging-related neurodegeneration and diabetes, Journal of Neuroscience |
Lane, R. F., St George-Hyslop, P., Hempstead, B. L., Small, S. A., Strittmatter, S. M., & Gandy, S. |
2012-10-10
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Alzheimer disease A tale of two prions, Prion |
Nussbaum, J. M., Seward, M. E., & Bloom, G. S. |
2012-09-10
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Disruption of the sleep-wake cycle and diurnal fluctuations of amyloid-beta in mice with Alzheimer’s disease pathology, Science Translational Medicine |
Roh, J. H., Huang, Y., Bero, A. W., Kasten, T., Stewart, F. R., Bateman, R. J., & Holtzman, D. M. |
2012-09-05
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Closing the case of APOE in multiple sclerosis: no association with disease risk in over 29,000 subjects, Journal of Medical Genetics |
Lill, C. M., Liu, T., Schjeide, B. M., Roehr, J. T., Akkad, D. A., Damotte, V., Alcina, A., Ortiz, M. A., … Bertram, L., Zipp, F. |
2012-09-01
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Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers, Biochimica et Biophysica Acta - General Subjects |
Arai, H., Glabe, C., & Luecke, H. |
2012-08-24
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General anesthetics and beta-amyloid protein, Progress in Neuro-Psychopharmacology & Biological Psychiatry |
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2012-08-13
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Latrepirdine stimulates autophagy and reduces accumulation of alpha-synuclein in cells and in mouse brain, Molecular Psychiatry |
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2012-08-07
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Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer’s mouse model, Molecular Psychiatry |
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2012-07-31
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Depletion of GGA1 and GGA3 mediates postinjury elevation of BACE1, Journal of Neuroscience |
Walker, K. R., Kang, E. L., Whalen, M. J., Shen, Y., & Tesco, G. |
2012-07-25
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Developing the “Next Generation: of genetic association databases for complex diseases, Human Mutation |
Lill, C. M., & Bertram, L. |
2012-07-12
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Anesthetic isoflurante increases phosphorylated tau levels mediated by caspase activation and A beta generation, PLoS One |
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2012-06-20
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Linking Lipids to Alzheimer’s Disease: cholesterol and beyond, Nature Reviews Neuroscience |
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2011-05-30
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2011-05-01
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2011-03-29
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2011-01-07
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Diabetes-associated SorCS1 regulates Alzheimer’s amyloid-beta metabolism: evidence for involvement of SorL1 and the Retromer Complex, Journal of Neuroscience |
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Genetic variants in PSEN2 and correlation to CSF beta-amyloid 42 levels in AD, Neurobiology of Aging |
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Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein, Journal of Biological Chemistry |
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2010-09-10
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The Acyl-coenzyme A: cholesterol Acyltransferase Inhibitor CI-1011 Reverses Diffuse Brain Amyloid pathology in aged amyloid precursor protein transgenic mice, Journal of Neuropathology & Experimental Neurology |
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Cognitively unimpaired HIV-positive subjects do not have icreased C-11 PiB A case-control study, Neurology |
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2010-06-30
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Systematic Analysis of Candidate Genes for Alzheimer’s Disease in a French, Genome-Wide Association Study, Journal of Alzheimer's Disease |
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2010-06-13
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Synopsis of preterm birth genetic association studies: the preterm birth genetics knowledge base (PTBGene), Public Health Genomics |
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Alzheimer’s disease Amyloid-beta links lens and brain pathology in Down syndrome, PLoS One |
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2010-05-20
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2010-05-19
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Memory impairment in transgenic Alzheimer mice requires cellular prion protein, Journal of Neuroscience |
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2010-05-05
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A beta-mediated NMDA receptor endocytosis in Alzheimer’s disease involves ubiquitination of the tyrosine phosphatase STEP61, Journal of Neuroscience |
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2010-04-28
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Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils., Nature Structural & Molecular Biology |
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2010-03-17
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The Alzheimer’s Disease-Associated Amyloid beta-Protein Is an Antimicrobial Peptide, PLoS One |
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2010-03-03
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2010-03-01
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2010-01-25
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Soluble fibrillar oligomer levels are elevated in Alzheimer’s disease brain and correlate with cognitive dysfunction, Neurobiology of Disease |
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2009-09-01
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Characterizing the Appearance and Growth of Amyloid plaques in APP/PS1 Mice, Journal of Neuroscience |
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2009-08-26
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Degradation of amyloid beta protein by purified myelin basic protein, Journal of Biological Chemistry |
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2009-08-19
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Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway, The FASEB Journal |
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2009-07-22
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2009-07-01
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Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in vitro., Biochemistry |
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2009-04-22
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Annular Protofibrils Are a Structurally and Functionally Distinct Type of Amyloid Oligomer, Journal of Biological Chemistry |
Kayed, R., Pensalfini, A., Margol, L., Sokolov, Y., Sarsoza, F., Head, E., Hall, J., & Glabe, C. |
2009-02-13
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GAB2 as an Alzheimer Disease Susceptibility Gene, Archives of Neurology |
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2009-02-01
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Assessment of Alzheimer’s disease case-control associations using family-based methods, Neurogenetics |
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2009-02-01
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Plug-based microfluidics with defined surface chemistry to miniaturize and control aggregation of amyloidogenic peptides, Angewandte Chemie (International ed. in English) |
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2009-01-30
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CDK5 is essential for adult hippocampal neurogenesis, Proceedings of the National Academy of Sciences of the United States of America |
Lagace, D. C., Benavides, D. R., Kansy, J. W., Mapelli, M., Greengard, P., Bibb, J. A., & Eisch, A. J. |
2008-11-18
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The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta protein level in vivo, Annals of Neurology |
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2008-11-11
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Structural Classification of Toxic Amyloid Oligomers, Journal of Biological Chemistry |
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2008-10-31
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Genome-wide Association Analysis Reveals Putative Alzheimer’s Disease Susceptibility Loci in Addition to APOE, American Journal of Human Genetics |
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2008-10-30
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Spatial memory is intact in aged rats after propofol anesthesia, Anesthesia & Analgesia |
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2008-10-01
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Association of GSK3b with Alzheimer disease and frontotemporal dementia, Archives of Neurology |
Schaffer, B. A., Bertram, L., Miller, B. L., Mullin, K., Weintraub, S., Johnson, N., Bigio, E. H., Mesulam, M., Wiedau-Pazos, M., Jackson, G. R., Cummings, J. L., Cantor, R. M., Levey, A. I., Tanzi, R. E., & Geschwind, D. H. |
2008-10-01
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Thirty years of Alzheimer’s disease genetics: the implications of systematic meta-analyses, Nature Reviews Neuroscience |
Bertram, L., & Tanzi, R. E. |
2008-10-01
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Evaluation of the Potential Excess of Statistically Significant Findings in Published Genetic Association Studies: Application to Alzheimer’s Disease, American Journal of Epidemiology |
Kavvoura, F. K., McQueen, M. B., Khoury, M. J., Tanzi, R. E., Bertram, L., & Ioannidis, J. P. |
2008-09-09
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Amyloid-beta dynamics correlate with neurological status in the injured human brain, Science |
Brody, D. L., Magnoni, S., Schwetye, K. E., Spinner, M. L., Esparza, T. J., Stocchetti, N., Zipfel, G. J., & Holtzman, D. M. |
2008-08-29
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Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation, Neuron |
Choi, S. H., Veeraraghavalu, K., Lazarov, O., Marler, S., Ransohoff, R. M., Ramirez, J. M., & Sisodia, S. S. |
2008-08-28
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Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers, Molecular Neurodegeneration |
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2007-09-26
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