These published papers resulted from Cure Alzheimer’s Fund support.
| Title | Researchers | Date |
|---|---|---|
| 3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes, ScienceDirect, Volume 180 | Marco Campisi, Yoojin Shin, Tatsuya Osaki, Cynthia Hajal, Valeria Chiono, Roger D.Kamm | July 14, 2018 |
| A 3D human neural cell culture system for modeling Alzheimer’s disease, Nature Protocols, 10(7) | Young Hye Kim, Se Hoon Choi, Carla D'Avanzo, Matthias Hebisch, Christopher Sliwinski, Enjana Bylykbashi, Kevin J Washicosky, Justin B Klee, Oliver Brüstle, Rudolph E Tanzi & Doo Yeon Kim | June 2015 |
| A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease, Nature Neuroscience | Joseph Park, Isaac Wetzel, Ian Marriott, Didier Dréau, Carla D’Avanzo, Doo Yeon Kim, Rudolph E. Tanzi & Hansang Cho | June 27, 2018 |
| A current view of Alzheimer’s disease, F1000 Biology Rep., 1 | Hooli BV, Tanzi RE | July 8, 2009 |
| A Functional Mouse Retroposed Gene Rps23r1 Reduces Alzheimer’s β-Amyloid Levels and Tau Phosphorylation, Neuron, 64(3) | Zhang Y-w, Liu Shijie, Zhang X, Li W-B, Chen Y, Huang X, Sun L, Luo W, Netzer WJ, Threadgill R, Wiegand G, Wang R, Cohen S, Greengard P, Liao F-F, Li L, Xu H | Nov 12, 2009 |
| A possible new role for Aβ in vascular and inflammatory dysfunction in Alzheimer’s disease, Thrombosis Research, 141(2) | Daria Zamolodchikov, Sidney Strickland | May 2016 |
| A Role for Presenilins in Autophagy Revisited: Normal Acidification of Lysosomes in Cells Lacking PSEN1 and PSEN2, The Journal of Neuroscience, 32(25) | Xulun Zhang1, Krassimira Garbett2, Karthikeyan Veeraraghavalu, Brian Wilburn, Reid Gilmore, Karoly Mirnics, and Sangram S. Sisodia | June 20, 2012 |
| A shortened Barnes maze protocol reveals memory deficits at 4-months of age in the triple-transgenic mouse model of Alzheimer’s disease, PLOS ONE, 8(11) | Attar A, Liu T, Chan WT, Hayes J, Nejad M, Lei K, Bitan G | November 13, 2013 |
| ABCA7 Deficiency Accelerates Amyloid- Generation and Alzheimer’s Neuronal Pathology, Neurobiology of Disease, 36(13) | Nobutaka Sakae, Chia-Chen Liu, Mitsuru Shinohara, Jessica Frisch-Daiello, Li Ma, Yu Yamazaki, Masaya Tachibana, Linda Younkin, Aishe Kurti, Minerva M. Carrasquillo, Fanggeng Zou, Daniel Sevlever, Gina Bisceglio, Ming Gan, Romain Fol, Patrick Knight, Miao Wang, Xianlin Han, John D. Fryer, Michael L. Fitzgerald, Yasumasa Ohyagi, Steven G. Younkin, Guojun Bu, and Takahisa Kanekiyo | 30 Mar 2016 |
| Accelerated Aβ Deposition in APPswe/PS1∆E9 Mice with Hemizygous Deletions of TTR (Transthyretin), J Neurosci, (26) | Choi SH, Leight SN, Lee VM-Y, Li T, Wong PC, Johson JA, Saraiva MJ, Sisodia SS | 2007 |
| Accelerating stem cell trials for Alzheimer’s disease, The Lancet Neurology, 15(2) | Joshua G Hunsberger, PhD, Mahendra Rao, MD, Joanne Kurtzberg, MD, Jeff W M Bulte, PhD, Anthony Atala, MD, Frank M LaFerla, PhD, Henry T Greely, JD, Akira Sawa,MD, Sam Gandy, MD, Lon S Schneider, MD, P Murali Doraiswamy, MBBS | February 2016 |
| Accelerating stem cell trials for Alzheimer’s disease, The Lancet Neurology | Joshua G Hunsberger, Ph.D., Mahendra Rao, M.D., Joanne Kurtzberg, M.D., Jeff W. M. Bulte, Ph.D., Anthony Atala, M.D., Frank M. LaFerla, Ph.D., Henry T. Greely, J.D., Akira Sawa, M.D., Sam Gandy, M.D., Lon S. Schneider, M.D., P. Murali Doraiswamy, M.B.B.S. | 15 December 2015 |
| Activation and Intrinsic γ-Secretase Activity of Presenilin 1, Proc. Natl. Acad. Sci USA, 50 | Kwangwook Ahn, Christopher C. Shelton, Yuan Tian, Xulun Zhang, M. Lane Gilchrist, Sangram S. Sisodia, and Yue-Ming Li | Oct 15, 2010 |
| Active and Passive Immunotherapy for Neurodegenerative Disorders, Annu Rev Neurosci., 31 | Brody DL, Holtzman DM | July 2008 |
| Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers, Nature Reviews Neurology | Steven T. DeKosky, Kaj Blennow, Milos D. Ikonomovic & Sam Gandy | April 2013 |
| Acute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid-beta levels in vitro and in vivo, Molecular Neurodegeneration, 4:51 | Steele JW, Kim HS, Cirrito JR, Verges DK, Restivo JL, Westaway D, Fraser P, Hyslop PSG, Sano M, Bezprozvanny I, Ehrlich ME, Holtzman DM, Gandy S | Dec 17, 2009 |
| Acute stress increases interstitial fluid amyloid-β via corticotropin-releasing factor and neuronal activity, Neurology, Vol. 75/no. 7 | Kang JE, Cirrito JR, Dong H, Csernansky JG, Holtzman DM | June 2007 |
| ADAM10 Missense Mutations Potentiate β-Amyloid Accumulation by Impairing Prodomain Chaperone Function, Neuron, 80(2) | Jaehong Suh, Se Hoon Choi, Donna M. Romano, Moira A. Gannon, Andrea N. Lesinski, Doo Yeon Kim, Rudolph E. Tanzi | Oct 16, 2013 |
| Age-dependent effect of apolipoprotein E4 on functional outcome after controlled cortical impact in mice, Journal of Cerebral Blood Flow & Metabolism, 31 | Mannix RC, Zhang J, Park J, Zhang X, Bilal K, Walker K, Tanzi RE, Tesco G, Whalen MJ | January 2011 |
| Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice, Sci Rep, 4 | Xu Z, Dong Y, Wang H, Culley DJ, Marcantonio ER, Crosby G, Tanzi RE, Zhang Y, Xie Z | January 20, 2014 |
| Age-Dependent, Non-Cell-Autonomous Deposition of Amyloid from Synthesis of β-Amyloid by Cells Other Than Excitatory Neurons, J Neurosci, 34(10) | Karthikeyan Veeraraghavalu, Can Zhang, Xiaoqiong Zhang, Rudolph E. Tanzi, and Sangram S. Sisodia | 5 March 2014 |
| Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction, The Journal of Biological Chemistry, 284(52) | Hata S, Fujishige S, Araki Y, Kato N, Araseki M, Nishimura M, Hartmann D, Saftig P, Fahrenholz F, Taniguchi M, Urakami K, Akatsu H, Martins R, Yamamoto K, Maeda M, Yamamoto T, Nakaya T, Gandy S, Suzuki T | Dec 25, 2009 |
| Altered sleep and EEG power in the P301S Tau transgenic mouse model, Ann Clin Transl Neurol, 4(3) | Jerrah K. Holth, Thomas E. Mahan, Grace O. Robinson, Andreia Rocha, David M. Holtzman | 15 Feb 2017 |
| Alzheimer disease: Solanezumab—prospects for meaningful interventions in AD?, Nature Reviews Neurology, 11 | Sam Gandy, Mary Sano | 03 November 2015 |
| Alzheimer’s Disease Amyloid-β Links Lens and Brain Pathology in Down Syndrome, PLoS ONE, 5(5) | Moncaster JA, Pineda R, Moir RD, Lu S, Burton MA, Ghosh JG, Ericsson M, Soscia SJ, Mocofanescu A, Folkerth RD, Robb RM, Kuszak JR, Clark JI, Tanzi RE, Hunter DG, Goldstein LE | May 20, 2010 |
| Alzheimer’s Disease Genetics: Current Status and Future Perspectives, International Review of Neurobiology, Vol. 84 | Bertram L | 2009 |
| Alzheimer’s disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation, Alzheimer's & Dementia, 13(4) | Wilbur Song, Basavaraj Hooli, Kristina Mullin, Sheng Chih Jin, Marina Cella, Tyler K. Ulland, Yaming Wang, Rudolph E. Tanzi, Marco Colonna | Apr 2017 |
| Alzheimer’s disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation, Alzheimer's & Dementia | Wilbur Song, Basavaraj Hooli, Kristina Mullin, Sheng Chih Jin, Marina Cella, Tyler K. Ulland, Yaming Wang, Rudolph Tanzi, Marco Colonna | 9 Aug 2016 |
| Alzheimer’s Disease-Associated Ubiquilin-1 Regulates Presenilin-1 Accumulation and Aggresome Formation, Traffic, 12(3) | Viswanathan J, Haapasalo A, Bottcher C, Miettinen R, Kurkinen KMA, Lu A, Thomas A, Maynard CJ, Romano D, Hyman BT, Berezovska O, Nertram L, Soininen H, Dantuma NP, Tanzi RE, Hiltunen M | Mar 12, 2011 |
| Alzheimer’s in 3D culture: Challenges and perspectives, BioEssays, 37(10) | Carla D'Avanzo, Jenna Aronson, Young Hye Kim, Se Hoon Choi, Rudolph E. Tanzi and Doo Yeon Kim | October 2015 |
| Alzheimer’s Disease-Associated b-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection, Neuron (Cell) | William A. Eimer,1,2 Deepak Kumar Vijaya Kumar,1,2 Nanda Kumar Navalpur Shanmugam,Alex S. Rodriguez, Teryn Mitchell, Kevin J. Washicosky, Bence Gyorgy, Xandra O. Breakefield, Rudolph E. Tanzi, and Robert D. Moir | July 11, 2018 |
| Alzheimer’s disease: the potential therapeutic role of the natural antibiotic amyloid-β peptide, Neurodegenerative Disease Management, 6(5) | Deepak Kumar Vijaya Kumar , William A Eimer , Rudolph E Tanzi and Robert D Moir | 7 Sep 2016 |
| Alzheimer’s genetics in the GWAS era: a continuing story of ‘replications and refutations’, Curr Neurol Neurosci Rep., 11(3) | Bertram, L | June 2011 |
| Amyloid and neurodegeneration: converging and diverging paths, Neurology, 81(20) | Klunk WE, Perani D | November 12, 2013 |
| Amyloid beta from axons and dendrites reduces local spine number and plasticity, Nature Neuroscience, 13(2) | Wei W, Nguyen L, Kessels HW, Hagiwara H, Sisodia S, Malinow R | Feb 2010 |
| Amyloid Precursor Protein Translation Is Regulated by a 3’UTR Guanine Quadruplex, PLOS ONE, 10(11) | Ezekiel Crenshaw, Brian P. Leung, Chun Kit Kwok, Michal Sharoni, Kalee Olson, Neeraj P. Sebastian, Sara Ansaloni, Reinhard Schweitzer-Stenner, Michael R. Akins, Philip C. Bevilacqua, Aleister J. Saunders | Nov 2015 |
| Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle, Science, 326(5955) | Kang JE, Lim MM, Bateman RJ, Lee JJ, Smyth LP, Cirrito JR, Fujiki N, Nishino S, Holtzman DM | Nov 13, 2009 |
| Amyloid-beta dynamics correlate with neurological status in the injured human brain, Science, 321(5893) | Brody DL, Magnoni S, Schwetye KE, Spinner ML, Esparza TJ, Stocchetti N, Zipfel GJ, Holtzman DM | Aug 29, 2008 |
| Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls, Ann. Neurol, 73(1) | Esparza TJ, Zhao H, Cirrito JR, Cairns NJ, Bateman RJ, Holtzman DM, Brody DL | January 1, 2013 |
| Amyloid-β Oligomers: Possible Role as Key Neurotoxins in Alzheimer’s Disease, Mount Sinai Joural of Medicine, 77 | Lublin AL, Gandy S | January 2010 |
| An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function, EMBO Molecular Medicine, 9(10) | Kai Schlepckow, Gernot Kleinberger, Akio Fukumori, Regina Feederle, Stefan F Lichtenthaler, Harald Steiner, Christian Haass | Oct 2017 |
| Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar, Br. J. Anaesth., 111(2) | Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW, Ma D, Orser BA, Planel E, Slikker W Jr, Soriano SG, Stratmann G, Vutskits L, Xie Z, Hemmings HC Jr | May 30, 2013 |
| Anesthetic Isoflurane Increases Phosphorylated Tau Levels Mediated by Caspase Activation and Aβ Generation, PLoS One, 7(6) | Yuanlin Dong, Xu Wu, Zhipeng Xu, Yiying Zhang, Zhongcong Xie | 2012 |
| Anesthetics Isoflurane and Desflurane Differently Affect Mitochondrial Function, Learning, and Memory, Annals of Neurology, Volume 71, Issue 5 | Yiying Zhang MD, MS1, Zhipeng Xu MD, PhD1, Hui Wang MD1,2, Yuanlin Dong MD, MS1, Hai Ning Shi PhD, DVM3, Deborah J. Culley MD4, Gregory Crosby MD4, Edward R. Marcantonio MD5, Rudolph E. Tanzi PhD.6, Zhongcong Xie MD, PhD1,* | February 24, 2012 |
| Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer, J Biol Chem, 284 | Kayed, R., Pensalfini, A., Margol, L., Sokolov, Y., Sarsoza, F., Head, E., Hall, J., and Glabe, C | February 13, 2009 |
| Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis, J Exp Med., 209(12) | Kim J, Eltorai AE, Jiang H, Liao F, Verghese PB, Kim J, Stewart FR, Basak JM, Holtzman DM | Nov 19, 2012 |
| Anti-tau antibody reduces insoluble tau and decreases brain atrophy, Annals of Clinical and Translational Neurology, 2(3) | Kiran Yanamandra, Hong Jiang, Thomas E. Mahan, Susan E. Maloney, David F. Wozniak, Marc I. Diamond and David M. Holtzman | March 2015 |
| Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APP(SWE)/PS1(Delta E9) murine model of Alzheimer’s disease, Scientific Reports, 7 | Myles R. Minter, Reinhard Hinterleitner, Marlies Meisel, Can Zhang, Vanessa Leone, Xiaoqiong Zhang, Paul Oyler-Castrillo, Xulun Zhang, Mark W. Musch, Xunuo Shen, Bana Jabri, Eugene B. Change, Rudolph E. Tanzi, Sangram Sisodia | 5 Sep 2017 |
| APOE ε4 and bapineuzumab: Infusing pharmacogenomics into Alzheimer disease therapeutics, Neurology, 73(24) | Kaufer D, Gandy S. | Dec 15, 2009 |
| APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes, Human Molecular Genetics, 26(14) | Jing Zhao, Mary D. Davis, Yuka A. Martens, Mitsuru Shinohara, Neill R. Graff-Radford, Steven G. Younkin, Zbigniew K. Wszolek, Takahisa Kanekiyo, Guojun Bu | 15 Jul 2017 |
| APOE2 eases cognitive decline during Aging: Clinical and preclinical evaluations, Annals of Neurology, 79(5) | Mitsuru Shinohara, Takahisa Kanekiyo, Longyu Yang, Duane Linthicum, Motoko Shinohara, Yuan Fu, Laura Price, Jessica L. Frisch-Daiello, Xianlin Han, John D. Fryer, Guojun Bu | 2 Mar 2016 |
| ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy, Nature | Yang Shi, Kaoru Yamada, Shane Antony Liddelow, Scott T. Smith, Lingzhi Zhao, Wenjie Luo, Richard M. Tsai, Salvatore Spina, Lea T. Grinberg, Julio C. Rojas, Gilbert Gallardo, Kairuo Wang, Joseph Roh, Grace Robinson, Mary Beth Finn, Hong Jiang, Patrick M. Sullivan, Caroline Baufeld, Michael W. Wood, Courtney Sutphen, Lena McCue, Chengjie Xiong, Jorge L. Del-Aguila, John C. Morris, Carlos Cruchaga, Alzheimer’s Disease Neuroimaging Initiative, Anne M. Fagan, Bruce L. Miller, Adam L. Boxer, William W. Seeley, Oleg Butovsky, Ben A. Barres, Steven M. Paul, David M. Holtzman | 20 Sep 2017 |
| Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2), The Journal of Biological Chemistry, 290(43) | Atagi Y, Liu CC, Painter MM, Chen XF, Verbeeck C, Zheng H, Li X, Rademakers R, Kang SS, Xu H, Younkin S, Das P, Fryer JD, Bu G | Oct 2015 |
| Apolipoprotein E4 Impairs Neuronal Insulin Signaling, Neuron, 96(1) | Na Zhao, Chia-Chen Liu, Alexandra J. Van Ingelgom, Yuka A. Martens, Cynthia Linares, Joshua A. Knight, Meghan M. Painter, Patrick M. Sullivan, Guojun Bu | 27 Sep 2017 |
| Assessment of Alzheimer’s disease case-control associations using family-based methods, Neurogenetics, DOI 10.1007/s10048-008-1051-3, | Schjeide BM, McQueen MB, Mullin K, DiVito J, Hogan MF, Parkinson M, Hooli B, Lange C, Blacker D, Tanzi RE, and Bertram L. | Feb 10, 2009 |
| Assessment of microRNA-related SNP effects in the 3′ untranslated region of theIL22RA2 risk locus in multiple sclerosis, Neurogenetics, 15(2) | Christina M. Lill, Marcel Schilling, Sara Ansaloni, Julia Schröder, Marian Jaedicke, Felix Luessi, Brit-Maren M. Schjeide, Andriy Mashychev, Christiane Graetz, Denis A. Akkad, Lisa-Ann Gerdes, Antje Kroner, Paul Blaschke, Sabine Hoffjan, Alexander Winkelmann, Thomas Dörner, Peter Rieckmann, Elisabeth Steinhagen-Thiessen, Ulman Lindenberger, Andrew Chan, Hans-Peter Hartung, Orhan Aktas, Peter Lohse, Mathias Buttmann, Tania Kümpfel, Christian Kubisch, Uwe K. Zettl, Joerg T. Epplen, Frauke Zipp, Lars Bertram | March 18 2014 |
| Association of GSK3B with Alzheimer’s Disease and Frontotemporal Dementia, Arch. Neurol., 65(10) | Schaffer B, Bertram L, Miller L, Mullin K, Weintraub S, Johnson N, Bigio E, Mesulam M, Wiedau-Pazos M, Jackson G, Cummings J, Cantor R, Levey A, Tanzi RE, and Geschwind D | October 2008 |
| Aβ-Mediated NMDA Receptor Endocytosis in Alzheimer’s Disease Involves Ubiquitination of the Tyrosine Phosphatase STEP, The Journal of Neuroscience, 30(17) | Kurup P, Zhang Y, Xu J, Venkitaramani DV, Haroutunian V, Greengard P, Nairn AC, Lombroso PJ | Apr 28 2010 |
| BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels, FASEB J, 27(6) | Sachse CC, Kim YH, Agsten M, Huth T, Alzheimer C, Kovacs DM, Kim DY | June 2013 |
| Bidirectional relationship between functional connectivity and amyloid-β deposition in mouse brain, J Neurosci., 32(13) | Bero AW, Bauer AQ, Stewart FR, White BR, Cirrito JR, Raichle ME, Culver JP, Holtzman DM | Mar 28, 2012 |
| BIN1 localization is distinct from Tau tangles in Alzheimer’s disease, Matters | Pierre De Rossi, Virginie Buggia-Prevot, Robert J Andrew, Sofia V Krause, Elizabeth Woo, Peter T Nelson, Peter Pytel, Gopal Thinakaran | 12 Jan 2017 |
| Caffeine suppresses beta-amyloid levels in plasma and brain of Alzheimer’s transgenic mice., Journal of Alzheimer's disease | Cao C, Cirrito JR, Lin X, Wang L, Verges DK, Dickson A, Mamcarz M, Zhang C, Mori T, Arendash GW, Holtzman DM, Potter H | July 2009 |
| CALHM1 P86L polymorphism does not alter amyloid-β or tau in cerebrospinal fluid, Neuroscience Letters, Volume 469, Issue 2 | Giedraitis V, Glaser A, Sarajarvi T, Brundin R, Gunnarsson MD, Schjeide B-M, Tanzi RE, Helisalmi S, Pirttila T, Kilander L, Lannfelt L, Soininen H, Bertram L, Ingelsson M, Hiltunen M | Jan 22 2010 |
| Call for participation in the neurogenetics consortium within the Human Variome Project, Neurogenetics, 12(3) | Haworth A, Bertram L, Carrera P, Elson JL, Braastad CD, Cox DW, Cruts M, den Dunnen JT, Farrer MJ, Fink JK, Hamed SA, Houlden H, Johnson DR, Nuytemans K, Palau F, Rayan DL, Robinson PN, Salas A, Schüle B, Sweeney MG, Woods MO, Amigo J, Cotton RG, Sobrido MJ | August 2011 |
| Casey CS, Atagi Y, Yamazaki Y, Shinohara M, Tachibana M, Fu Y, Bu G, Kanekiyo T, Journal of Biological Chemistry, 290(22) | May 2015 | |
| Cdk5 is essential for adult hippocampal neurogenesis, Proceedings of the National Academy of Science, Vol. 105 No. 47 | Lagace D, Benavides D, Kansy J, Mapelli M, Greengard P, Bibb J, Eisch A | October 9, 2008 |
| Cellular pharmacology of protein kinase Mζ (PKMζ) contrasts with its in vitro profile: implications for PKMζ as a mediator of memory, J Biol Chem., 287(16) | Wu-Zhang AX, Schramm CL, Nabavi S, Malinow R, Newton AC | Apr 13, 2012 |
| Cellular Prion Protein Mediates the Toxicity of β-Amyloid Oligomers, Archives of Neurology, 66(11) | Nygaard HB, Strittmatter SM | Nov 2009 |
| Cerebrospinal Fluid Aβ to Tau Ratio and Postoperative Cognitive Change, Annals of Surgery, Ann Surg 2013;00 | Zhongcong Xie, MD, PhD, Sayre McAuliffe, Celeste A. Swain, Sarah A. P. Ward, Catherine A. Crosby, Hui Zheng, Janet Sherman, Yuanlin Dong, Yiying Zhang, Neelakantan Sunder, Dennis Burke, Kevin Washicosky, Rudolph E. Tanzi, and Edward R. Marcantonio | 5/10/2013 |
| Cerebrospinal fluid sTREM2 levels are associated with gray matter volume increases and reduced diffusivity in early Alzheimer’s disease, Alzheimer's & Dementia, 12(12) | Juan Domingo Gispert, Marc Suárez-Calvet, Gemma C. Monté, Alan Tucholka, Carles Falcon, Santiago Rojas, Lorena Rami, Raquel Sánchez-Valle, Albert Lladó, Gernot Kleinberger, Christian Haass, José Luis Molinuevo | Dec 2016 |
| Changes in the Expression of the Alzheimer’s Disease- Associated Presenilin Gene in Drosophila Heart Leads to Cardiac Dysfunction, NIHPA Author Manuscripts, 8/3 | A. Li, C. Zhou, J. Moore, P. Zhang, T.-H. Tsai, H.-C. Lee, D.M. Romano, M.L. McKee, D.A. Schoenfeld, M.J. Serra,3 K. Raygor, H.F. Cantiello, J.G. Fujimoto, and R.E. Tanzi | May 1, 2011 |
| Chapter Three – Screening and Characterization Strategies for Nanobodies Targeting Membrane Proteins, Methods in Enzymology, 584 | S. Veugelen, M. Dewilde, B. De Strooper, L. Chávez-Gutiérrez | 2017 |
| Characterization and Molecular Profiling of PSEN1 Familial Alzheimer’s Disease iPSC-Derived Neural Progenitors, PLoS ONE, 9(1) | Andrew A. Sproul, Samson Jacob, Deborah Pre, Soong Ho Kim, Michael W. Nestor, Miriam Navarro-Sobrino, Ismael Santa-Maria, Matthew Zimmer, Soline Aubry, John W. Steele, David J. Kahler, Alex Dranovsky, Ottavio Arancio, John F. Crary, Sam Gandy, and Scott A. Noggle | Jan 8 2014 |
| Characterization of a subpopulation of developing cortical interneurons from human iPSCs within serum-free embryoid bodies, American Journal of Physiology - Cell Physiology, 308(3) | Michael W. Nestor, Samson Jacob, Bruce Sun, Deborah Prè, Andrew A. Sproul, Seong Im Hong, Chris Woodard, Matthew Zimmer, Vorapin Chinchalongporn, Ottavio Arancio, Scott A. Noggle | Feb 2015 |
| Characterization of tau prion seeding activity and strains from formaldehyde-fixed tissue, Acta Neuropathologica Communications, 5 | Sarah K. Kaufman, Talitha L. Thomas, Kelly Del Tredici, Heiko Braak, Marc I. Diamond | 7 Jun 2017 |
| Characterizing Gene and Protein Crosstalks in Subjects at Risk of Developing Alzheimer’s Disease: A New Computational Approach, Processes, 5(3) | Kanchana Padmanabhan, Kelly Nudelman, Steve Harenberg, Gonzalo Bello, Dongwha Sohn, Katie Shpanskaya, Priyanka Tiwari Dikshit, Pallavi S. Yerramsetty, Rudolph E. Tanzi, Andrew J. Saykin, Jeffrey R. Petrella, P. Murali Doraiswamy, Nagiza F. Samatova, Alzheimer’s Disease Neuroimaging Initiative | Sep 2017 |
| Characterizing the Appearance and Growth of Amyloid Plaques in APP/PS1 Mice, The Journal of Neuroscience, 29(34) | Yan P, Bero AW, Cirrito JR, Xiao Q, Hu X, Wang Y, Gonzales E, Holtzman DM, Lee J-M | Aug 26 2009 |
| Chronic Progressive Neurodegeneration in a Transgenic Mouse Model of Prion Disease, Frontiers in Neuroscience, 10 | Nina Fainstein, Dvir Dori, Kati Frid, Alexa T. Fritz, Ilona Shapiro, Ruth Gabizon, and Tamir Ben-Hur | 11 Nov 2016 |
| Chronic Traumatic Encephalopathy: Diagnosing the Repetitively Injured Brains of Athletes and Soldiers, Current Research: Concussion | Dara L. Dickstein, Effie M. Mitsis, Corey Fernandez, Mariel Pullman, Patrick R. Hof, Jennifer Short, Gregory Elder, Barry Jordan, Stephen Ahlers, Heidi Bender, Martin L. Goldstein, John F. Crary, Kristen Dams-O’Connor, Wayne Gordon, Robert Cantu, Karin Knesaurek, Mary Sano, James R. Stone6, Lale Kostakoglu, Steven T. DeKosky, and Sam Gandy | December 2015 |
| Clinical and imaging assessment of acute combat mild traumatic brain injury in Afghanistan, Neurology, 85(3) | Octavian Adam, M.D., Christine L. Mac Donald, Ph.D., Dennis Rivet, M.D., John Ritter, M.D., Todd May, D.O., Maria Barefield, O.T.D., Josh Duckworth, M.D., Donald LaBarge, M.D., Dean Asher, M.D., Benjamin Drinkwine, M.D., Yvette Woods, Ph.D., Michael Connor, Psy.D. and David L. Brody, M.D., Ph.D. | 21 July 2015 |
| Clinical presentation of chronic traumatic encephalopathy, Neurology, 81(13) | Stern RA, Daneshvar DH, Baugh CM, Seichepine DR, Montenigro PH, Riley DO, Fritts NG, Stamm JM, Robbins CA, McHale L, Simkin I, Stein TD, Alvarez VE, Goldstein LE, Budson AE, Kowall NW, Nowinski CJ, Cantu RC, McKee AC | September 24, 2013 |
| Closing the case of APOE in multiple sclerosis: no association with disease risk in over 29,000 subjects, J Med Genet., 49(9) | Lill CM, Liu T, Schjeide BM, Roehr JT, Akkad DA, Damotte V, Alcina A, Ortiz MA, Arroyo R, Lopez de Lapuente A, Blaschke P, Winkelmann A, Gerdes LA, Luessi F, Fernadez O, Izquierdo G, Antigüedad A, Hoffjan S, Cournu-Rebeix I, Gromöller S, Faber H, Liebsch M, Meissner E, Chanvillard C, Touze E, Pico F, Corcia P; ANZgene Consortium, Dörner T, Steinhagen-Thiessen E, Baeckman L, Heekeren HR, Li SC, Lindenberger U, Chan A, Hartung HP, Aktas O, Lohse P, Kümpfel T, Kubisch C, Epplen JT, Zettl UK, Fontaine B, Vandenbroeck K, Matesanz F, Urcelay E, Bertram L, Zipp F | September 2012 |
| Cognitive trajectories associated with β-amyloid deposition in the oldest-old without dementia, Neurology, 80(15) | Snitz BE, Weissfeld LA, Lopez OL, Kuller LH, Saxton J, Singhabahu DM, Klunk WE, Mathis CA, Price JC, Ives DG, Cohen AD, McDade E, Dekosky ST | April 9, 2013 |
| Comprehensive research synopsis and systematic meta-analyses in Parkinson’s disease genetics: The PDGene database, PLoS Genet., 8(3) | Lill CM, Roehr JT, McQueen MB, Kavvoura FK, Bagade S, Schjeide BM, Schjeide LM, Meissner E, Zauft U, Allen NC, Liu T, Schilling M, Anderson KJ, Beecham G, Berg D, Biernacka JM, Brice A, DeStefano AL, Do CB, Eriksson N, Factor SA, Farrer MJ, Foroud T, Gasser T, Hamza T, Hardy JA, Heutink P, Hill-Burns EM, Klein C, Latourelle JC, Maraganore DM, Martin ER, Martinez M, Myers RH, Nalls MA, Pankratz N, Payami H, Satake W, Scott WK, Sharma M, Singleton AB, Stefansson K, Toda T, Tung JY, Vance J, Wood NW, Zabetian CP; 23andMe Genetic Epidemiology of Parkinson's Disease Consortium; International Parkinson's Disease Genomics Consortium; Parkinson's Disease GWAS Consortium; Wellcome Trust Case Control Consortium 2), Young P, Tanzi RE, Khoury MJ, Zipp F, Lehrach H, Ioannidis JP, Bertram L | March 2012 |
| CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2(N141I) neurons, Acta Neuropathologica Communications, 5 | Maitane Ortiz-Virumbrales, Cesar L. Moreno, Ilya Kruglikov, Paula Marazuela, Andrew Sproul, Samson Jacob, Matthew Zimmer, Daniel Paull, Bin Zhang, Eric E. Schadt, Michelle E. Ehrlich, Rudolph E. Tanzi, Ottavio Arancio, Scott Noggle, Sam Gandy | 27 Oct 2017 |
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