2023
The Golgi apparatus is required for normal function of all cells. This proposal is aimed at determining whether reversal of Golgi fragmentation by overexpression of a key Golgi protein (called GRASP55) in the mouse brain can modulate the behavioral, molecular and histological features of two mouse models of Alzheimer’s disease.
$230,000
Studies of Alternative Neurodegenerative Pathways, Translational
Sam Gandy, M.D., Ph.D.
Yanzhuang Wang, Ph.D.