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Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Title Researchers Date
Innovation breakthrough in the Alzheimer’s disease pharmaceutical industry, npg drug discovery Cheng, H., Kang, L., Xu, Y., Tanzi, R. E., Zhang, C., & Wang, C. 2026-03-02
Liver exerkine reverses aging- and Alzheimer’s-related memory loss via vasculature, Cell Bieri, G., Pratt, K. J. B., Fuseya, Y., Aghayev, T., Sucharov, J., ... Yang, A. C., Casaletto, K. B., & Villeda, S. A. 2026-02-28
Matching heterogeneous cohorts by projected principal components reveals two novel Alzheimer’s disease-associated genes in the Hispanic population, Alzheimer's & Dementia Willett, J. D. S., Waqas, M., Naumenko, S., Mullin, K., Hecker, J., Bertram, L., Lange, C., Vlachos, I., Hide, W., Tanzi, R. E., & Prokopenko, D. 2026-02-27
Immunity in Alzheimer’s disease: From mechanisms to therapies, Immunity Chen, X., Holtzman, D. M., & Colonna, M. 2026-02-26
Increased cerebrospinal fluid YKL-40 concentration in hip fracture patients with delirium, Brain Communications Berntsen, T., Blennow, K., Zetterberg, H., ... Neerland, B. E. 2026-02-25
Identification of distinct and shared biomarker panels in different manifestations of cerebral small-vessel disease through proteomic profiling, Nature Aging Hristovska, I., Pichet Binette, A., Kumar, A., Wennström, M., Gaiteri, C., Karlsson, L., Strandberg, O., Janelidze, S., van Westen, D., Stomrud, E., Palmqvist, S., Ossenkoppele, R., Mattsson-Carlgren, N., Vogel, J. W., & Hansson, O. 2026-02-24
Spatially resolved transcriptomic profiling identifies distinct signatures in parenchymal and vascular microenvironments in Alzheimer’s Disease with Cerebral Amyloid Angiopathy, Alzheimer's & Dementia Chimal-Juárez, E., Jury-Garfe, N., Gomez-Isaza, L., Troncoso, J. C., & Lasagna-Reeves, C. A. 2026-02-22
Golgi Fragmentation as a Potential Link Between SARS-CoV-2 Infection and Alzheimer’s Disease: Mechanisms and Implications for Neurodegeneration in Long COVID, The Golgi Network, Volume II Wang, Y., & Gandy, S. 2026-02-21
TREM2 and APOE are dispensable for microglial clearance of dying neurons revealed by in vivo imaging, iScience https://doi.org/10.1016/j.isci.2025.114559 2026-02-20
Loss of REST associated with Alzheimer’s disease pathology is ameliorated by NAD, Brain Lagartos-Donate, M. J., Escobar-Doncel, B., Zhang, S. Q., Pan, J. P., Villaseca González, N., … Fang, E. F. 2026-02-19
Plasma neurofilament light chain is associated with clinical instability in chronic autoimmune neuropathies, Scientific Reports Glāzere, I., Roddate, M., Žukova, V., Kurjāne, N., Blennow, K., Zetterberg, H., & Ķēniņa, V. 2026-02-16
Therapeutic targeting of neuroimmune mechanisms in neurodegeneration, Nature Reviews Drug Discovery Monroe, K. M., Hong, S., Lewcock, J. W., & Yang, A. C. 2026-02-16
Shake and bake: a robust and cost-effective proteomic sample preparation workflow for plasma and cerebrospinal fluid, Clinical Proteomics Rönnholm, J., Weiner, S., Fuchs, J., Thorsell, A., Sihlbom, C., Dugom, L., Easton, A., Zetterberg, H., & Gobom, J. 2026-02-15
Plasma ATN biomarkers across the alzheimer’s disease continuum in a Chilean community- and clinic-based cohort, Alzheimer's Research & Therapy Orellana, P., Henríquez, F., Cabral-Miranda, F., Hernandez, H., Ferreira, P. C. L., … Zetterberg, H., Pascoal, T. A., Duran-Aniotz, C., & Slachevsky, A. 2026-02-14
Blood-based AT(N) biomarkers for Alzheimer’s disease and frontotemporal lobar degeneration in Latin America, Nature Aging Caviedes, A., Cabral-Miranda, F., Orellana, P., Hernández, H., Henríquez, F., ... Zetterberg, H., … Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat) 2026-02-13
Lipidome and Proteome of Astrocyte and Microglia ApoE Lipoprotein Reveal Differences Based on Cell Type and ApoE Isoform, Journal of Lipid Research Strickland, M. R., Wang, Z., Golden, L. R., Wang, H., Lu, P., Ren, Y., Tabor, G. T., Zhao, N., Ulrich, J. D., Han, X., Peng, J., & Holtzman, D. M. 2026-02-13
Circadian timing of the dystrophin associated complex across the brain and body, Fluids and Barriers of the CNS Morse, I., Nedergaard, M., & Hablitz, L. M. 2026-02-12
Longitudinal changes of blood β-synuclein in cognitively unimpaired, mild cognitive impairment and sporadic Alzheimer´s disease, Alzheimer's Research & Therapy Oeckl, P., Abu-Rumeileh, S., Weise, C. M., Otto, M., & Alzheimer’s Disease Neuroimaging Initiative 2026-02-11
APOE4 drives maladaptive heterogeneity and immunometabolic responses of astrocytes, Journal of Neuroinflammation Goulding, D. S., Williams, H. C., Gorman, A. A., Devanney, N. A., Harrison, D. A., Walsh, A. E., Tuck, T., Zajac, D. J., Macauley, S. L., Estus, S., Tcw, J., A Johnson, L., & Morganti, J. M. 2026-02-11
Levetiracetam prevents Aβ production through SV2a-dependent modulation of APP processing in Alzheimer’s disease models, Science Translational Medicine Rao, N. R., Santiago-Marrero, I., DeGulis, O., Nomura, T., Goyal, K., Lee, S., Hark, T. J., Dynes, J. C., Dexter, E. X., Dulewicz, M., Ge, J., Upadhyay, A., Fornasiero, E. F., Vassar, R., Hanrieder, J., Contractor, A., & Savas, J. N. 2026-02-11