These published papers resulted from Cure Alzheimer’s Fund support.
Graff-Radford, J., Syrjanen, J. A., Vemuri, P., Lowe, V. J., ... Petersen, R. C., Hansson, O., & Jack, C. R., Jr Predictive Value of Plasma Biomarkers in Tau-PET Transitions, Annals of Neurology, September 10, 2025, Read More
Inoue, Y., Wang, H., Heckman, M. G., Ren, Y., White, L. J., Lu, W., Wang, P., Tcw, J., Koga, S., Alnobani, A., DeTure, M., Murray, M. E., Petersen, R. C., Dickson, D. W., Bu, G., Han, X., & Kanekiyo, T. Impact of APOE on cerebrovascular lipid profile in Alzheimer’s disease, Acta Neuropathologica, October 8, 2025, Read More
Salvadó, G., Janelidze, S., Bali, D., Dolado, A. O., Therriault, J., … Petersen, R. C., Jack, C. R., Jr., Schindler, S. E., Suárez-Calvet, M., Ossenkoppele, R., Hansson, O., for the ADNI, ALFA, and PREVENT-AD Study Groups Plasma Phosphorylated Tau 217 to Identify Preclinical Alzheimer Disease, JAMA Neurology, September 15, 2025, Read More
Cogswell, P. M., Wiste, H. J., Therneau, T. M., Griswold, M. E., Mattsson-Carlgren, N., Palmqvist, S., Binette, A. P., Stomrud, E., Bateman, R. J., Barthelemy, N., Braunstein, J. B., West, T., Verghese, P. B., Machulda, M. M., Graff-Radford, J., Algeciras-Schimnich, A., Lowe, V. J., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Petersen, R. C., Hansson, O. & Jack, C. R., Jr Association of plasma Alzheimer’s disease biomarkers with cognitive decline in cognitively unimpaired individuals, Alzheimer's & Dementia, August 29, 2025, Read More
Imam, F., Saloner, R., Vogel, J. W., Krish, V., Abdel-Azim, G., Ali, M., An, L., Anastasi, F., Bennett, D., Pichet Binette, A., Boxer, A. L., Bringmann, M., Burns, J. M., Cruchaga, C., Dage, J. L., Farinas, A., Ferrucci, L., Finney, C. A., Frasier, M., Hansson, O., … Petersen, R. C., ... Wyss-Coray, T., ... Global Neurodegeneration Proteomics Consortium (GNPC) The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging, Nature Medicine, July 15, 2025, Read More
Moscoso, A., Heeman, F., Raghavan, S., Costoya-Sánchez, A., van Essen, M., ... Ossenkoppele, R., ...Hansson, O., ... Petersen, R. C., … PREVENT-AD Research Group, the Harvard Aging Brain Study, the LEADS Consortium, and the Alzheimer’s Disease Neuroimaging Initiative Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity, JAMA, June 16, 2025, Read More
Garbarino, V. R., Palavicini, J. P., Melendez, J., Barthelemy, N. R., He, Y., Kautz, T. F., Lopez-Cruzan, M., Mathews, J. J., Xu, P., Zhang, B., Saliba, A., Ragi, N., Sharma, K., Mason, D., Johnson, S., Hendrix, S., Craft, S., Petersen, R. C., … Bateman, R. J., Gonzales, M. M., & Orr, M. E. Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer’s disease, Neurotherapeutics, April 23, 2025, Read More
Ossenkoppele, R., Salvadó, G., Janelidze, S., Pichet Binette, A., Bali, D., ... Bateman R. J., ... Petersen, R. C, Jack, C. R., Jr, & Hansson, O. Plasma p-tau217 and tau-PET predict future cognitive decline among cognitively unimpaired individuals: implications for clinical trials, Nature Aging, March 28, 2025, Read More
Li, Z., Martens, Y. A., Ren, Y., Jin, Y., Sekiya, H., ... Petersen, R. C., Kanekiyo, T., … Bu, G., & Zhao, N. APOE genotype determines cell-type-specific pathological landscape of Alzheimer’s disease, Neuron, March 11, 2025, Read More
2. Therriault, J., Janelidze, S., Benedet, A. L., Ashton, N. J., Arranz Martínez, J., Gonzalez-Escalante, A., Bellaver, B., Alcolea, D., Vrillon, A., Karim, H., Mielke, M. M., … Petersen, R. C., … Zetterberg, H., … Hansson, O., & Rosa-Neto, P. Diagnosis of Alzheimer’s disease using plasma biomarkers adjusted to clinical probability, Nature Aging, November 12, 2024, Read More
Raulin, A. C., Doss, S. V., Heckman, M. G., Craver, E. C., Li, Z., Ikezu, T. C., Sekiya, H., Liu, C. C., Martens, Y. A., Rosenberg, C. L., Kuchenbecker, L. A., DeTure, M., Reichard, R. R., Nguyen, A. T., Constantopoulos, E., Larsen, R. A., Kounaves, E. K., Murray, M. E., Dickson, D. W., Petersen, R. C., Bu, G., Kanekiyo, T. Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer’s disease, Acta Neuropathologica Communications, February 9, 2024, Read More
Liu, C. C., Murray, M. E., Li, X., Zhao, N., Wang, N., Heckman, M. G., Shue, F., Martens, Y., Li, Y., Raulin, A. C., Rosenberg, C. L., Doss, S. V., Zhao, J., Wren, M. C., Jia, L., Ren, Y., Ikezu, T. C., Lu, W., Fu, Y., Caulfield, T., Trottier, Z.A., Knight, J., Chen, Y., Linares, C., Wang, X., Kurti, A., Asmann, Y.W., Wszolek, Z.K., Smith, G.E., Vemuri, P., Kantarci, K., Knopman, D.S., Lowe, V.J., Jack, C.R. Jr, Parisi, J.E., Ferman, T.J., Boeve, B.F., Graff-Radford, N.R., Petersen, R.C., Younkin, S.G., Fryer, J.D., Wang, H., Han, X., Frieden, C., Dickson, D.W., Ross, O.A., Bu, G. APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia, Science Translational Medicine, September 29, 2021, Read More
Li, Z., Heckman, M. G., Kanekiyo, T., Martens, Y. A., Day, G. S., Vassilaki, M., Liu, C. C., Bennett, D. A., Petersen, R. C., Zhao, N., & Bu, G. Clinicopathologic Factors Associated With Reversion to Normal Cognition in Patients With Mild Cognitive Impairment, Neurology, May 17, 2022, Read More
Yamazaki, Y., Shinohara, M., Shinohara, M., Yamazaki, A., Murray, M. E., Liesinger, A. M., Heckman, M. G., Lesser, E. R., Parisi, J. E., Petersen, R. C., Dickson, D. W., Kanekiyo, T., & Bu, G. Selective loss of cortical endothelial tight junction proteins during Alzheimer’s disease progression, Brain, February 15, 2019, Read More
Liu, C. C., Yamazaki, Y., Heckman, M. G., Martens, Y. A., Jia, L., Yamazaki, A., Diehl, N. N., Zhao, J., Zhao, N., DeTure, M., Davis, M. D., Felton, L. M., Qiao, W., Li, Y., Li, H., Fu, Y., Wang, N., Wren, M., Aikawa, T., Holm, M. L., Oue, H., Linares, C., Allen, M., Carrasquillo, M.M., Murray, M.E., Petersen, R.C., Ertekin-Taner, N., Dickson, D.W., Kanekiyo, T., Bu, G. Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer’s disease, Alzheimer's & Dementia, August 22, 2020, Read More
Shinohara, M., Koga, S., Konno, T., Nix, J., Shinohara, M., Aoki, N., Das, P., Parisi, J. E., Petersen, R. C., Rosenberry, T. L., Dickson, D. W., & Bu, G. Distinct spatiotemporal accumulation of N-truncated and full-length amyloid-beta(42) in Alzheimer’s disease., Brain, November 17, 2017, Read More
Barroeta-Espar, I., Weinstock, L. D., Perez-Nievas, B. G., Meltzer, A. C., Siao Tick Chong, M., Amaral, A. C., Murray, M. E., Moulder, K. L., Morris, J. C., Cairns, N. J., Parisi, J. E., Lowe, V. J., Petersen, R. C., Kofler, J., Ikonomovic, M. D., López, O., Klunk, W. E., … Gomez-Isla, T. Distinct Cytokine Profiles in human brains resilient to Alzheimer’s pathology, Neuroiology of Disease, October 15, 2018, Read More