Mast cell deficiency improves cognition and enhances disease-associated microglia in 5XFAD mice

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Vascular endothelial growth factor associated dissimilar cerebrovascular phenotypes in two different mouse models of Alzheimer’s Disease

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A Small molecule screen exposes mTOR signaling pathway involvement in radiation-induced apoptosis

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Inhibition of Tau aggregation with BSc3094 reduces Tau and decreases cognitive deficits in rTg4510 mice

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Isoflurane facilitates synaptic NMDA receptor endocytosis in mice primary neurons

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Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance

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The Battle Against Alzheimer’s: Mind & Soul

“Snap out of it!” —Loretta Castorini, in the film Moonstruck When Loretta Castorini, played by Cher, slapped troubled Ronny Cammareri, played by Nicholas Cage, in the seminal film Moonstruck, the brash smack to the face struck a chord with troubled souls, then and now. Just get over it! Right? Not so easy to snap ...

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MANBA, CXCR5, SOX8, RPS6KB1, ZBTB46 are genetic risk loci for multiple sclerosis

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Molecular tweezers targeting transthyretin amyloidosis

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Assessment of separation methods for extracellular vesicles from human and mouse brain tissues and human cerebrospinal fluids

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