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Krista L. Moulder, Ph.D.

Assistant Professor of Neurology; Executive Director, Charles F. and Joanne Knight Alzheimer’s Disease Research Center, Washington University School of Medicine in St. Louis

Krista L. Moulder, Ph.D., is Associate Professor of Neurology and Executive Director of the Charles F. & Joanne Knight Alzheimer’s Disease Research Center (Knight ADRC) at Washington University School of Medicine.  Dr. Moulder obtained her BA in Biochemistry, Molecular Biology, and Cell Biology from Northwestern University in 1993, and her Ph.D. in Molecular Cell Biology from Washington University in 2001.  Her research interests have included neuronal cell death, neurodegenerative cell signaling pathways, electrophysiology, and glutamatergic and GABAergic hippocampal neurotransmission.  Dr. Moulder has authored 34 peer-reviewed publications and has a current H-index of 25.  Dr. Moulder is a member of the Society for Neuroscience.

In 2001, Dr. Moulder departed bench science to join the Knight ADRC Administration Core.  In this role, she oversees two Program Project Grants as well as the ADRC P50 Center Grant under the Directorship of Dr. John C. Morris.  She recently completed a three-year term as an elected member of the Administrators’ Steering Committee for all 31 National Institute on Aging-funded Alzheimer’s Disease Centers.  She also led a study on lumbar puncture practices across these Centers, which was published in 2017.

In service to Washington University, Dr. Moulder lectures for the medical students’ Principles of Pharmacology course, and guest lectures for Psychiatry residents and Physical Therapy students.  She also is a full board member of the Institutional Review Board.

To learn more about the Knight ADRC, follow the center on social media @wuadrc.

Related Research:

Characterization of Alzheimer’s Disease Molecular Biomarker Profiles Throughout the Pathobiological Continuum Krista L. Moulder 2020-02-18 Scientific Directions for the Exploration of Racial Disparities in Alzheimer’s Disease Krista L. Moulder 2018-07-24

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Project Description Researchers Funding
Characterization of Alzheimer’s Disease Molecular Biomarker Profiles Throughout the Pathobiological Continuum 2019, 2020, 2022, 2023, 2024

$481,768
Scientific Directions for the Exploration of Racial Disparities in Alzheimer’s Disease 2018

$79,594.20

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Xiong, C., Luo, J., Wolk, D. A., Shaw, L. M., Roberson, E. D., Murchison, C. F., Henson, R. L., Benzinger, T. L. S., Bui, Q., Agboola, F., Grant, E., Gremminger, E. N., Moulder, K. L., Geldmacher, D. S., Clay, O. J., Babulal, G., Cruchaga, C., Holtzman, D. M., Bateman, R. J., Morris, J. C., Schindler, S. E. Baseline levels and longitudinal changes in plasma Aβ42/40 among Black and white individuals, Nature Communications, July 2, 2024, Read More

Schindler, S. E., Cruchaga, C., Joseph, A., McCue, L., Farias, F. H. G., Wilkins, C. H., Deming, Y., Henson, R. L., Mikesell, R. J., Piccio, L., Llibre-Guerra, J. J., Moulder, K. L., Fagan, A. M., Ances, B. M., Benzinger, T. L. S., Xiong, C., Holtzman, D. M., & Morris, J. C. African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants, Neurology Genetics, March 4, 2021, Read More

Schindler, S. E., Karikari, T. K., Ashton, N. J., Henson, R. L., Yarasheski, K. E., West, T., Meyer, M. R., Kirmess, K. M., Li, Y., Saef, B., Moulder, K. L., Bradford, D., Fagan, A. M., Gordon, B. A., Benzinger, T. L. S., Balls-Berry, J., Bateman, R. J., Xiong, C., Zetterberg, H., Blennow, K., … Morris, J. C. Effect of Race on Prediction of Brain Amyloidosis by Plasma Aβ42/Aβ40, Phosphorylated Tau, and Neurofilament Light, Neurology, April 21, 2022, Read More

Barroeta-Espar, I., Weinstock, L. D., Perez-Nievas, B. G., Meltzer, A. C., Siao Tick Chong, M., Amaral, A. C., Murray, M. E., Moulder, K. L., Morris, J. C., Cairns, N. J., Parisi, J. E., Lowe, V. J., Petersen, R. C., Kofler, J., Ikonomovic, M. D., López, O., Klunk, W. E., … Gomez-Isla, T. Distinct Cytokine Profiles in human brains resilient to Alzheimer’s pathology, Neuroiology of Disease, October 15, 2018, Read More

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