Rik Ossenkoppele, Ph.D.

Associate Professor in Translational Neuroscience and Principal Investigator, the Alzheimercenter Amsterdam of the Amsterdam UMC and at Lund University in Sweden

Rik Ossenkoppele is an associate professor in Translational Neuroscience and PI at the Alzheimercenter Amsterdam of the Amsterdam UMC and at Lund University in Sweden. He works on the intersection between neuroimaging, biomarkers and cognition in Alzheimer’s disease. His main motivation is to contribute to improving the diagnostic/prognostic work-up (short-term goal) and curing AD (long-term goal). Dr. Ossenkoppele received several prestigious prices (e.g., the European Grand Prix for Research on the Foundation of Alzheimer’s Disease [2019], the Young Investigator Research award from Alzheimer Nederland [2020] and the Queen Silvia Research Prize [2021]) and research grant (e.g., an ERC starting grant and various dementia research grants). He is also an associate editor for Alzheimer’s Research & Therapy, program committee member for several AD and FTD imaging conferences and Vice Chair for the Atypical AD Professional Interest Areas of the Alzheimer Association.



@RikOssenkoppele, @biofinder_study

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Salvadó, G., Horie, K., Barthélemy, N. R., Vogel, J. W., Pichet Binette, A., Chen, C. D., Aschenbrenner, A. J., Gordon, B. A., Benzinger, T. L. S., Holtzman, D. M., Morris, J. C., Palmqvist, S., Stomrud, E., Janelidze, S., Ossenkoppele, R., Schindler, S. E., Bateman, R. J., & Hansson, O. Disease staging of Alzheimer’s disease using a CSF-based biomarker model, Nature Aging, March 21, 2024, Read More

Barthélemy, N. R., Salvadó, G., Schindler, S., He, Y., Janelidze, S., Collij, L. E., Saef, B., Henson, R. L., Chen, C. D., Gordon, B. A., Li, Y., La Joie, R., Benzinger, T. L. S., Morris, J. C., Mattsson-Carlgren, N., Palmqvist, S., Ossenkoppele, R., Rabinovici, G. D., Stomrud, E., Bateman, R. J. & Hansson, O. Highly Accurate Blood Test for Alzheimer’s Disease Comparable or Superior to Clinical CSF Tests, Nature Medicine, February 21, 2024, Read More

Young, A. L., Vogel, J. W., Robinson, J. L., McMillan, C. T., Ossenkoppele, R., Wolk, D. A., Irwin, D. J., Elman, L., Grossman, M., Lee, V. M., Lee, E. B., & Hansson, O. Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies, Brain, May 8, 2023, Read More

Zheng, L., Rubinski, A., Denecke, J., Luan, Y., Smith, R., Strandberg, O., Stomrud, E., Ossenkoppele, R., Svaldi, D. O., Higgins, I. A., Shcherbinin, S., Pontecorvo, M. J., Hansson, O., Franzmeier, N., Ewers, M., & Alzheimer's Disease Neuroimaging Initiative Combined Connectomics, MAPT Gene Expression, and Amyloid Deposition to Explain Regional Tau Deposition in Alzheimer Disease, Annals of Neurology, October 14, 2023, Read More

Bocancea, D. I., Svenningsson, A. L., van Loenhoud, A. C., Groot, C., Barkhof, F., Strandberg, O., Smith, R., Alzheimer’s Disease Neuroimaging Initiative, La Joie, R., Rosen, H. J., Pontecorvo, M. J., Rabinovici, G. D., van der Flier, W. M., Hansson, O., & Ossenkoppele, R. Determinants of cognitive and brain resilience to tau pathology: a longitudinal analysis, Brain, March 27, 2023, Read More

Coomans, E. M., van Westen, D., Pichet Binette, A., Strandberg, O., Spotorno, N., Serrano, G. E., Beach, T. G., Palmqvist, S., Stomrud, E., Ossenkoppele, R., & Hansson, O. Interactions between vascular burden and amyloid-β pathology on trajectories of tau accumulation, Brain, September 18, 2023, Read More

Horie, K., Salvadó, G., Barthélemy, N. R., Janelidze, S., Li, Y., He, Y., Saef, B., Chen, C. D., Jiang, H., Strandberg, O., Pichet Binette, A., Palmqvist, S., Sato, C., Sachdev, P., Koyama, A., Gordon, B. A., Benzinger, T. L. S., Holtzman, D. M., Morris, J. C., Mattsson-Carlgren, N., … Bateman, R. J. CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease, Nature Medicine, July 13, 2023, Read More

Mattsson-Carlgren, N., Collij, L. E., Stomrud, E., Pichet Binette, A., Ossenkoppele, R., Smith, R., Karlsson, L., Lantero-Rodriguez, J., Snellman, A., Strandberg, O., Palmqvist, S., Ashton, N. J., Blennow, K., Janelidze, S., & Hansson, O. Plasma Biomarker Strategy for Selecting Patients With Alzheimer Disease for Antiamyloid Immunotherapies, JAMA Neurology, December 4, 2023, Read More