Will Restoration of Normal Glymphatic Function Slow Progression of Cognitive Decline and Amyloid Plaques in a Murine Alzheimer Model?

2016

This proposal will map glymphatic function as a function of aging in a mouse model of Alzheimer’s disease. We also will test the hypothesis that exercise and improved sleep can slow the progression of cognitive decline by improving glymphatic clearance.

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Using Epigenetics to Characterize the Regulation of Cellular States in Microglia that Contribute to Alzheimer’s Disease Pathology

Bradley Hyman, | 2020

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Paola Bovolenta, Pilar Esteve, | 2020

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Characterization of Alzheimer’s Disease Molecular Biomarker Profiles Throughout the Pathobiological Continuum

Shirley Wray,

An Innovative Study of the Pupil Light Reflex in Alzheimer’s Disease

Will Restoration of Normal Glymphatic Function Slow Progression of Cognitive Decline and Amyloid Plaques in a Murine Alzheimer Model?

Funding to Date

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Researchers

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