Will Restoration of Normal Glymphatic Function Slow Progression of Cognitive Decline and Amyloid Plaques in a Murine Alzheimer Model?

2016, 2017

This proposal will map glymphatic function as a function of aging in a mouse model of Alzheimer’s disease. We also will test the hypothesis that exercise and improved sleep can slow the progression of cognitive decline by improving glymphatic clearance.


Funding to Date

$300,000

Focus

Foundational, Production of New Animal/Cellular Models of AD

Researchers

Maiken Nedergaard, M.D., D.M.Sc.


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