Patient-Based Structural and Functional Biology of Tauopathies

2021

We seek to generate models depicting the unique structures characteristic of abnormal forms of tau protein that accumulate in Alzheimer’s disease and related disorders. In addition, using new structural models, we have generated novel resources to provide both a greater understanding of key events that drive disease, as well as facilitated testing of potential therapies.


Funding to Date

$172,500

Focus

Studies of Tau, Translational

Researchers

Leonard Petrucelli, Ph.D.