Frank LaFerla, Ph.D.

Frank LaFerla, PhD serves as PPM Scientific Advisor at Signum Biosciences, Inc. Dr. LaFerla is the Chancellor’s Professor of Neurobiology and Behavior; Director of the Institute for Memory Impairments and Neurological Disorders at the University of California Irvine. He serves as Member of the Advisory Board at Sonexa Therapeutics, Inc. Dr. LaFerla and colleagues developed the triple transgenic (3xTg) mouse model of AD, which has become among the most important tools available to AD researchers. His research efforts have resulted in a number of academic distinctions and awards including the Zenith Fellow Award, the Alzheimer’s Association, the Promising Work Award and the MetLife Foundation Awards for Medical Research.

Related Research:

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Project Description Researchers Funding
Mouse Model for Non-Generic Alzheimer’s Disease 2010


Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Baglietto-Vargas, D., Forner, S., Cai, L., Martini, A. C., Trujillo-Estrada, L., Swarup, V., ... LaFerla, F. M. Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer’s disease-like pathology, Nature Communications, April 23, 2021, Read More

Hunsberger, J. G., Rao, M., Kurtzberg, J., Bulte, J. W. M., Atala, A., LaFerla, F. M., Greely, H. T., Sawa, A., Gandy, S., Schneider, L. S., & Doraiswamy, P. M. Accelerating Stem Cell Trials for Alzheimer’s Disease, Lancet Neurology, December 17, 2015, Read More