These projects were made possible from Cure Alzheimer's Fund support.
Project Description | Researchers | Funding |
---|---|---|
T-Cell Modulation of Microglia to Treat Alzheimer’s Disease |
2024, 2025 $402,468 |
|
Targeting the Microbiome and Innate Immunity in Alzheimer’s Disease |
2022, 2023 $402,500 |
|
Targeting the Microbiome and Microglia in Alzheimer’s Disease |
2019, 2021 $345,000 |
These published papers resulted from Cure Alzheimer’s Fund support.
Kimura, K., Subramanian, A., Yin, Z., Khalilnezhad, A., Wu, Y., He, D., Dixon, K. O., Chitta, U. K., Ding, X., Adhikari, N., Guzchenko, I., Zhang, X., ... Selkoe, D., Weiner, H. L., Blurton-Jones, M., Cruchaga, C., … Butovsky, O., Kuchroo, V. K. Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease, Nature, April 9, 2025, Read More
Hu, D., Chen, M., Li, X., Daley, S., Morin, P., Han, Y., Hemberg, M., Weiner, H. L., & Xia, W. ApoE ε4-dependent Alteration of CXCR3 + CD127+ CD4+ T cells associates with elevated plasma neurofilament light chain in Alzheimer’s disease, Journal of Alzheimer's Disease, March 20, 2025, Read More
Brandao, W., Jain, N., Yin, Z., Kleemann, K. L., … Ulrich, J. D., Blurton-Jones, M., Ilin, I., Weiner., H. L., Holtzman, D. M., Butovsky, O. Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy, Science Translational Medicine, January 15, 2025, Read More
Rosenzweig, N., Kleemann, K. L., Rust, T., Carpenter, M., Grucci, M., Aronchik, M., Brouwer, N., Valenbreder, I., Cooper-Hohn, J., Iyer, M., Krishnan, R. K., Sivanathan, K. N., Brandão, W., Yahya, T., Durao, A., Yin, Z., Chadarevian, J. P., Properzi, M. J., Nowarski, R., Davtyan, H., Weiner, L. H., Blurton Jones, M., … Butovsky, O. Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease, Nature Medicine, July 3, 2024, Read More
Wasén, C., Beauchamp, L. C., Vincentini, J., Li, S., LeServe, D. S., Gauthier, C., Lopes, J. R., Moreira, T. G., Ekwudo, M. N., Yin, Z., da Silva, P., Krishnan, R. K., Butovsky, O., Cox, L. M., & Weiner, H. L. Bacteroidota inhibit microglia clearance of amyloid-beta and promote plaque deposition in Alzheimer’s disease mouse models, Nature Communications, May 8, 2024, Read More