Mathieu Bourdenx, Ph.D.

Senior Research fellow, UK Dementia Research Institute (UKDRI), University College London


Dr. Mathieu Bourdenx is a senior research fellow at the UK Dementia Research Institute (UKDRI) at University College London, in London. He obtained his Ph.D. in Neuroscience and Neuropharmacology from the University of Bordeaux (France) in 2015 under the supervision of Drs. Erwan Bezard and Benjamin Dehay. He then joined the laboratory of Prof. Ana Maria Cuervo in Albert Einstein College of Medicine in New York in 2017 for postdoctoral training and recently joined (Dec. 2021) the laboratory of Prof. Karen Duff at UKDRI.

Dr. Bourdenx is interested in understanding protein aggregation and associated proteostasis defects in the context of aging and age-related diseases such as Alzheimer’s disease and Parkinson’s disease. More specifically, he focuses on the mechanisms of aggregate formation through defects of the autophagy/lysosomal system and how lack of degradation ultimately contributes to disease onset and progression.

Dr. Bourdenx has been the recipient of the Monique Garnier-Semancik award, the University of Bordeaux doctoral award for the best Ph.D. thesis and the Junior Investigator in Neuroscience Research Award from the Albert Einstein College of Medicine in 2018.