Associate Professor of General Pathology, University of Padova, Italy
Dr. Paola Pizzo got her Bc.S. in Biology at the University of Padova in 1988. She did her Ph.D. in Experimental Pathology at the same University, with Prof. Francesco Di Virgilio, investigating the new role of ATP as an extracellular signaling molecule. She then moved to Israel for her post-doc at the Weizmann Institute of Science, in the lab of Profs. David Yaffe and Uri Nudel, working on DP71, a new dystrophin gene product. Back to Padova as Assistant Professor, she worked together with Prof. Tullio Pozzan, defining the role of different pathways of cellular Ca2+ homeostasis in multiple physiological and pathological conditions. In 2000, she started her own project on Ca2+ handling alterations and mitochondria dysfunction in familial Alzheimer’s disease (FAD), unraveling the role of mutated FAD-linked presenilin 2 and its impact on neuronal metabolism and function.