The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer’s disease mouse model

February 9, 2022

Bruce Lamb, Gary Landreth, Mathew Blurton-Jones

Marina Ryan

Marina Ryan, 85, passed away peacefully at home surrounded by her family on June 25, 2024, following a 15-year battle with Alzheimer’s Disease. Born in Edinburgh, Scotland in 1938, Marina was the daughter of the late Alberto and Maria (Ferrari) Beccarelli. She came to the United States in 1961 as a ...

July 10, 2024

Ronald Peter Bianchini, Sr.

Ronald Peter Bianchini, Sr., age 88, of Somerset, NJ, passed away peacefully on Tuesday, February 6, 2024, surrounded by his most beloved family members, including his devoted wife of 62 years, Elaine Bianchini (Santoro). On February 5, 1936, Ronald was born in the Marine Park neighborhood of Brooklyn, NY, on the ...

February 8, 2024

Kathleen Gallivan Casazza

Kathleen “Kathy” Marie Gallivan Casazza passed away on Friday, December 15, at the age of 75 surrounded by family. Kathy was born on March 13, 1948, at Brady Maternity Hospital in Albany, N.Y. to Charles Gillette Gallivan and Dorothy Margaret Carroll Gallivan. She grew up in Guilderland, N.Y. and attended Marylrose ...

January 9, 2024

Kathleen Durkin

Durkin, Kathleen M, of Rockville Centre, New York, passed on January 21st, 2025 in her 85th year. Beloved mother of James, Kathie, Michael, Richie, & Tisha. Cherished grandmother of Jennifer, Michelle, Angela, Stephanie, James, Jason, Alex, Jill, Nicholas, Jacquelin, Julianna, & Zachary. Great grandmother to Lindsey, Siles, Matthew, Alanna, Finn, Ella, ...

February 14, 2025

Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease

October 23, 2020

Hansang Cho, Mathew Blurton-Jones

Bahaa Elgendy

Dr. Elgendy is an Associate Professor at Washington University School of Medicine in St. Louis. He received his Ph.D. working with Dr. Alan Katritzky at the University of Florida. Following his doctoral studies, Dr. Elgendy pursued postdoctoral research at Scripps Research Institute. At the Elgendy lab, their primary objective is to ...

January 16, 2024

Bahaa Elgendy

APOE and Alzheimer’s Disease

Co-chaired by three members of CAF’s Research Consortium—Drs. David Holtzman, Sam Sisodia and Rudy Tanzi—participants included all the other members of the Research Consortium (except Virginia Lee, who had a prior commitment) and several invited guests whose records of research include valuable insights into this relationship. The guests were Michael ...

April 21, 2010

New Research Reveals Common Genetic Risk Factor Linking Alzheimer’s Disease and Type 2 Diabetes

Potential for New Therapies to Treat both Diseases The discovery of a molecular mechanism linking Alzheimer’s disease and Type 2 Diabetes could lead to exciting new drugs to treat both devastating diseases, according to new research published this week in The Journal of Neuroscience.  Researchers found that the gene for ...

September 30, 2010

NPR Features Interview of Sam Gandy on CAF Funded Research Linking Alzheimer’s and Type II Diabetes

National Public Radio’s Alan Chartock, from WAMC, hosted Dr. Sam Gandy on his show today. The hour long program focused on Gandy’s recent Cure Alzheimer’s Fund supported discovery of the link between Alzheimer’s and Type II Diabetes. Dr. Gandy, Cure Alzheimer’s Fund Research Consortium member is a Mount Sinai Professor ...

December 23, 2010