While many were anxious to accept initial findings showing a drug known as Targretinās ātoo good to be trueā lab results with Alzheimerās disease, subsequent attempts to confirm and replicate the original data regarding the ability of Targretin to remove amyloid plaques, the cardinal lesion of the disease, have largely ...
May 24, 2013
A new Alzheimer’s disease (AD) model suggests that defects in the blood-brain barrier (BBB) play a key role in worsening amyloid plaques and neurofibrillary tangles, and that therapies to reduce gaps in the BBB hold promise for treatment of the disease. The new model uses āmicrofluidicsā to examine how a layer ...
October 9, 2019
Cure Alzheimerās Fund and Rotary joined forces this fall to fund research into why women are more likely to get Alzheimerās disease than men. The two organizations granted a total of $375,000 to the lab of Rudy Tanzi, Ph.D., at Massachusetts General Hospital. Tanzi, who serves as the Research Consortium ...
December 13, 2016
January 30, 2024
John Patrick “Pat” Walker, 78, of West Newton, passed away peacefully, Thursday, Feb. 2, 2023, at Arden Courts of Monroeville, with his family by his side. He was born Oct. 7, 1944, in Greensburg, the son of the late John Ward Walker and Lucille (Fmura) Walker. In addition to his ...
February 27, 2023
Most researchers agree that the amyloid beta peptide, A-beta, is a key player in Alzheimerās disease pathology. Exactly how it is involved is still unclear; but attention is now shifting from A-beta as the main component of the tell-tale amyloid plaques to the basic component in A-beta āoligomersā or clumps ...
March 2, 2010
Riding for a Remedy During the summer of 2019, Alexander Schmidt & Augustus Snyder will attempt to cycle the entire Trans American Trail unassisted from Virginia Beach, VA to Astoria, OR. This 4,227-mile tour from the Atlantic to Pacific Ocean is inspired by a dream theyāve shared since undergrad and their ...
December 21, 2018
On Feb. 6, we visited the site of the Cure Alzheimerās Fund Research Consortiumās annual meeting to hear the latest progress from our Genes to Therapiesā¢ Steering Committee. This webinar is moderated by David Shenk, author of āThe Forgetting,ā and features each of the researchers on the G2T Steering Committee. Learn ...
February 6, 2015
Authors Dr. Rudy Tanzi, Chair of the Cure Alzheimerās Fund Research Leadership Group, and Anne B. Parson, science journalist, published Decoding Darkness in 2001. Taken from the description of the book on Amazon.com, āWorking from the intriguing hypothesis that Alzheimer’s dementia is the result of a renegade protein-beta amyloid-Tanzi and ...
October 30, 2020
September 24, 2017
