Investigation of Certain Properties of Mitochondria Membranes Related to AD

2008

While the mechanism of Aβ cytotoxicity remains contentious, evidence is accumulating that membrane permiabilization plays a key role in the pathological activity of the peptide. This study will focus on role of Aβ oligomerization in the Aβ-mediated disruption of lipid bilayers.


Funding to Date

$200,000

Focus

Foundational Genetics

Researchers

Robert Moir, Ph.D.


Rudolph Tanzi, Ph.D.