2008
The specific hypothesis behind the proposed research is that presenilin 1 regulates cell fate determination of adult neural progenitor cells by interfering with instructive intercellular signals prevailing within the neural progenitor cell niche, and that expression of the familial AD-linked presenilin 1adversely affects this process.
$100,000
Biomarkers/Diagnostics/Studies of Risk & Resilience, Foundational
Sangram S. Sisodia, Ph.D.
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