Sex Differences in Alzheimer’s Disease Progression: Framingham Heart Study

2020, 2022

The promise of personalized medicine includes understanding sex differences in health and disease. It has been well documented that women have a higher risk of developing Alzheimer’s disease compared with men, but this is not simply because women on average live to older age than men. This proposal capitalizes on the 70 years of health-related data from the Framingham Heart Study, combining with traditional and machine learning analytic methods, to determine what combination of factors can explain sex differences in Alzheimer’s disease risk and progression.

Funding to Date



Biomarkers/Diagnostics/Studies of Risk & Resilience, Foundational


P. Murali Doraiswamy, M.B.B.S.

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