Will Restoration of Normal Glymphatic Function Slow Progression of Cognitive Decline and Amyloid Plaques in a Murine Alzheimer Model?

2016

This proposal will map glymphatic function as a function of aging in a mouse model of Alzheimer’s disease. We also will test the hypothesis that exercise and improved sleep can slow the progression of cognitive decline by improving glymphatic clearance.


Funding to Date

$150,000

Focus

Pathological Pathways and Systems, Translational Research

Researchers

Maiken Nedergaard, M.D., D.M.Sc.