Investigation of Certain Properties of Mitochondria Membranes Related to AD


While the mechanism of Aβ cytotoxicity remains contentious, evidence is accumulating that membrane permiabilization plays a key role in the pathological activity of the peptide. This study will focus on role of Aβ oligomerization in the Aβ-mediated disruption of lipid bilayers.

Funding to Date



Studies of Alternative Neurodegenerative Pathways, Translational


Rudy Tanzi, Ph.D.

Robert Moir, Ph.D.