These projects were made possible from Cure Alzheimer's Fund support.
These published papers resulted from Cure Alzheimer’s Fund support.
Liang, Y., Lee, D. Y. W., Zhen, S., Sun, H., Zhu, B., Liu, J., Lei, D., Lin, C. J., Zhang, S., Jacques, N. A., Quinti, L., Ran, C., Wang, C., Griciuc, A., Choi, S. H., Dai, R. H., Efferth, T., Tanzi, R. E., & Zhang, C. Natural medicine HLXL targets multiple pathways of amyloid-mediated neuroinflammation and immune response in treating alzheimer’s disease, Phytomedicine, May 13, 2022, Read More
McAlpine, C. S., Park, J., Griciuc, A., Kim, E., Choi, S. H., Iwamoto, Y., Kiss, M. G., Christie, K. A., Vinegoni, C., Poller, W. C., Mindur, J. E., Chan, C. T., He, S., Janssen, H., Wong, L. P., Downey, J., Singh, S., Anzai, A., Kahles, F., Jorfi, M., Feruglio, P.F., Sadreyev, R. I., Weissleder, R., Kleinstiver, B. P., Nahrendorf, M., Tanzi, R. E., & Swirski, F. K. Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease, Nature, July 14, 2021, Read More
Griciuc, A., & Tanzi, R. E. The role of innate immune genes in Alzheimer’s disease, Current Opinion in Neurology, April 1, 2021, Read More
Griciuc, A., Federico, A. N., Natasan, J., Forte, A. M., McGinty, D., Nguyen, H., Volak, A., LeRoy, S., Gandhi, S., Lerner, E. P., Hudry, E., Tanzi, R. E., & Maguire, C. A. Gene therapy for Alzheimer’s Disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation., Human Molecular Genetics, August 17, 2020, Read More
Griciuc, A., Patel, S., Federico, A. N., Choi, S. H., Innes, B. J., Oram, M. K., Cereghetti, G., McGinty, D., Anselmo, A., Sadreyev, R. I., Hickman, S. E., El Khoury, J., Colonna, M., & Tanzi, R. E. TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer’s Disease, Neuron, July 10, 2019, Read More
Zhang, C., Griciuc, A., Hudry, E., Wan, Y., Quinti, L., Ward, J., Forte, A. M., Shen, X., Ran, C., Elmaleh, D. R., & Tanzi, R. E. Cromolyn Reduces Levels of the Alzheimer’s Disease-Associated Amyloid Beta Protein by Promoting microglial Phagocytosis, Scientific Reports, January 18, 2018, Read More
Griciuc, A., Serrano-Pozo, A., Parrado, A. R., Lesinski, A. N., Asselin, C. N., Mullin, K., Hooli, B., Choi, S. H., Hyman, B. T., & Tanzi, R. E. Alzheimer’s disease risk gene CD33 inhibits microglial uptake of amyloid beta, Neuron, May 22, 2013, Read More