Cure Alzheimer's Fund Cure Alzheimer's Fund

Cheryl Wellington, Ph.D.

Professor, Department of Pathology and Laboratory Medicine, University of British Columbia

Dr. Cheryl Wellington is Professor and Vice Chair of Research, Department of Pathology and Laboratory Medicine, Djavad Mowafaghian Center for Brain Health, University of British Columbia. Her translational research interests include Alzheimer’s Disease, Traumatic Brain Injury and neurology blood biomarkers. Dr. Wellington holds multiple leadership and executive positions in the dementia and neurotrauma communities, including the Canadian Consortium for Neurodegeneration in Aging, Cure Alzheimer’s Fund, Canadian Traumatic Brain Injury Research Consortium, Canadian Concussion Network, and the International Initiative on Traumatic Brain Injury Research.

Related Research:

Fleming APOE Consortium: Effect of Cholesteryl Ester Transfer Protein Activity on Amyloid and Cerebrovascular Pathologies in Animal Models of Alzheimer’s Disease Cheryl Wellington 2022-11-16 APOE Consortium: Toward Developing High-Density Lipoprotein Enriched in Apolipoprotein E as a Potential Biomarker and Therapeutic Targeting Vascular Contributions to Alzheimer’s Disease Cheryl Wellington 2017-07-25

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Project Description Researchers Funding
Fleming APOE Consortium: Effect of Cholesteryl Ester Transfer Protein Activity on Amyloid and Cerebrovascular Pathologies in Animal Models of Alzheimer’s Disease 2022, 2024

$575,000
APOE Consortium: Toward Developing High-Density Lipoprotein Enriched in Apolipoprotein E as a Potential Biomarker and Therapeutic Targeting Vascular Contributions to Alzheimer’s Disease 2017, 2018, 2020, 2021

$1,249,222

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

10. Kloske, C. M., Belloy, M. E., Blue, E. E., Bowman, G. R., … Gate, D., … , Iadecola, C., Johnson, L. A., Kanekiyo, T., … Lamb, B.T., … Marcora, E., … Morganti, J. M., … Ramachandran, K. V., … Tsai, L. H., … Ulrich, J. D., van der Kant, R., … Wellington, C. L., … Zhao, N., Bu, G., Goate, A. M., Holtzman, D. M. Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference, Alzheimer's & Dementia, July 19, 2024, Read More

Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., Jacobs, R. E., Doubal, F. N., Ramirez, J., Black, S. E., Nedergaard, M., Benveniste, H., Dichgans, M., Iadecola, C., Love, S., Bath, P. M., … Zlokovic, B. V. Vascular dysfunction — The disregarded partner of Alzheimer’s disease, Alzheimer's & Dementia, January 1, 2019, Read More

Cable, J., Holtzman, D. M., Hyman, B. T., Tansey, M. G., Colonna, M., Kellis, M., Brinton, R. D., Albert, M., Wellington, C. L., Sisodia, S. S., & Tanzi, R. E. Alternatives to Amyloid for Alzheimer’s Disease Therapies-A Symposium Report, Annals of the New York Academy of Sciences, May 29, 2020, Read More

Robert, J., Button, E. B., Martin, E. M., McAlary, L., Gidden, Z., Gilmour, M., Boyce, G., Caffrey, T. M., Agbay, A., Clark, A., Silverman, J. M., Cashman, N. R., & Wellington, C. L. Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E, Molecular Neurodegeneration, March 25, 2020, Read More

Robert, J., Weilinger, N. L., Cao, L. P., Cataldi, S., Button, E. B., Stukas, S., Martin, E. M., Seibler, P., Gilmour, M., Caffrey, T. M., Rowe, E. M., Fan, J., MacVicar, B., Farrer, M. J., & Wellington, C. L. An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases, Molecular Neurodegeneration, November 19, 2020, Read More

Poliakova, T., & Wellington, C. L. Roles of peripheral lipoproteins and cholesteryl ester transfer protein in the vascular contributions to cognitive impairment and dementia, Molecular Neurodegenration, November 16, 2023, Read More

Chen, L. Y. C., Hoiland, R. L., Stukas, S., Wellington, C. L., & Sekhon, M. S. Assessing the importance of interleukin-6 in COVID-19, The Lancet Respiratory Medicine, February 9, 2021, Read More

Button, E. B., Cheng, W. H., Barron, C., Cheung, H., Bashir, A., Cooper, J., Gill, J., Stukas, S., Baron, D. C., Robert, J., Rowe, E. M., Cripton, P. A., & Wellington, C. L. Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury, Alzheimer's Research & Therapy, March 7, 2021, Read More

Hoiland, R. L., Fergusson, N. A., Mitra, A. R., Griesdale, D. E. G., Devine, D. V., Stukas, S., Cooper, J., Thiara, S., Foster, D., Chen, L. Y. C., Lee, A. Y. Y., Conway, E. M., Wellington, C. L., & Sekhon, M. S. The association of ABO blood group with indices of disease severity and multiorgan dysfunction in COVID-19, Blood Advances, October 14, 2020, Read More

Chen, L. Y. C., Biggs, C. M., Jamal, S., Stukas, S., Wellington, C. L., & Sekhon, M. S. Soluble interleukin-6 receptor in the COVID-19 cytokine storm syndrome, Cell Reports Medicine, April 19, 2021, Read More

Chen, L. Y. C., Hoiland, R. L., Stukas, S., Wellington, C. L., & Sekhon, M. S. Confronting the controversy: Interleukin-6 and the COVID-19 cytokine storm syndrome, European Respiratory Journal, October 1, 2020, Read More

Zlokovic, B. V., Gottesman, R. F., Bernstein, K. E., Seshadri, S., McKee, A., Snyder, H., Greenberg, S. M., Yaffe, K., Schaffer, C. B., Yuan, C., Hughes, T. M., Daemen, M. J., Williamson, J. D., González, H. M., Schneider, J., Wellington, C. L., Katusic, Z. S., Stoeckel, L., Koenig, J. I., Corriveau, R. A., Fine, L., Galis, Z. G., Reis, J., Wright, J.D., & Chen, J. Vascular contributions to cognitive impairment and dementia (VCID): A report from the 2018 National Heart, Lung, and Blood Institute and National Institute of Neurological Disorders and Stroke Workshop, Alzheimer's & Dementia, October 8, 2020, Read More

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