These projects were made possible from Cure Alzheimer's Fund support.
| Project Description | Researchers | Funding |
|---|---|---|
| Alzheimer’s Disease Tau Consortium: Deep Mass Spectrometry Profiling of Tau Aggregates in Alzheimer’s Disease and Other Tauopathies |
2022, 2024 $575,000 |
These published papers resulted from Cure Alzheimer’s Fund support.
Meda, F. J., Dittrich, A., Skoog, I., Kern, S., Leckey, C., Wild, E. J., Paterson, R. W., Brinkmalm, G., Andreasson, U., Blennow, K., Zetterberg, H., & Kvartsberg, H. Alpha-internexin as a brain-specific neurodegeneration marker: development and validation of a novel CSF assay, Journal of Neurobiology, October 6, 2025, Read More
Acta Neuropathologica Reversible tau hyperphosphorylation in hibernation: a blood biomarker and brain tissue study, Acta Neuropathologica, September 29, 2025, Read More
Wood, J. I., Dulewicz, M., Szadziewska, A., Weiner, S., Ge, J., Stringer, K., Desai, S., Fenson, L., Piotrowska, D., Brinkmalm, G., Koutarapu, S., Hajar, H. B., Blennow, K., Zetterberg, H., Cummings, D. M., Savas, J. N., Edwards, F. A., & Hanrieder, J. Isotope-encoded spatial biology identifies plaque-age-dependent maturation and synaptic loss in an Alzheimer’s disease mouse model, Nature Communications, September 1, 2025, Read More
Montoliu-Gaya, L., Salvadó, G., Therriault, J., Nilsson, J., Janelidze, S., Weiner, S., Ashton, N. J., Benedet, A. L., Rahmouni, N., Lantero-Rodriguez, J., Mattsson-Carlgren, N., Palmqvist, S., Brinkmalm, G., Stomrud, E., Zetterberg, H., Gobom, J., Rosa-Neto, P., Blennow, K., & Hansson, O. Plasma tau biomarkers for biological staging of Alzheimer’s disease, Nature Aging, August 22, 2025, Read More
Montoliu-Gaya, L., Valeriano-Lorenzo, E., Ashton, N. J., López-González, F. J., Lantero-Rodriguez, J., Ruiz-González, A., Pastor, A. B., Frades, B., Zea-Sevilla, M. A., Valentí, M., Ruiz-Valderrey, P., Saiz, L., Burgueño-García, I., López-Martínez, M. J., Del Ser, T., Brinkmalm, G., Zetterberg, H., … Sánchez-Juan, P. Plasma tau biomarkers are distinctly associated with tau tangles and decreased with Lewy body pathology, Alzheimer's & Dementia, August 12, 2025, Read More
Becker, B., Gobom, J., Brinkmalm, G., Andreasson, U., Meda, F. J., Zetterberg, H., & Blennow, K. Novel insights into the molecular nature of neurofilament light polypeptide species in cerebrospinal fluid, Brain Communications, April 2, 2025, Read More
Watamura, N., Foiani, M. S., Bez, S., Bourdenx, M., Santambrogio, A., Frodsham, C., Camporesi, E., Brinkmalm, G., Zetterberg, H., , … Duff, K. E., Saido, T. C. In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds, Nature Neuroscience, December 24, 2024, Read More
Lantero-Rodriguez, J., Camporesi, E., Montoliu-Gaya, L., Gobom, J., Piotrowska, D., Olsson, M., Burmann, I. M., Becker, B., Brinkmalm, A., Burmann, B. M., Perkinton, M., Ashton, N. J., Fox, N. C., Lashley, T., Zetterberg, H., Blennow, K., & Brinkmalm, G. Tau protein profiling in tauopathies: a human brain study, Molecular Neurodegeneration, July 19, 2024, Read More
Kasri, A., Camporesi, E., Gkanatsiou, E., Boluda, S., Brinkmalm, G., Stimmer, L., Ge, J., Hanrieder, J., Villain, N., Duyckaerts, C., Vermeiren, Y., Pape, S. E., Nicolas, G., Laquerrière, A., De Deyn, P. P., Wallon, D., Blennow, K., Strydom, A., Zetterberg, H., & Potier, M. C. Amyloid-β peptide signature associated with cerebral amyloid angiopathy in familial Alzheimer’s disease with APPdup and Down syndrome, Acta Neuropathologica, July 18, 2024, Read More
Gobom, J., Brinkmalm, A., Brinkmalm, G., Blennow, K., & Zetterberg, H. Alzheimer’s disease biomarker analysis using targeted mass spectrometry, Molecular & Cellular Proteomics, January 20, 2024, Read More