Henrik Zetterberg, M.D., Ph.D.

Professor of Neurochemistry, University of Gothenburg, Sweden and University College London, UK; Clinical Chemist, Sahlgrenska University Hospital, Gothenburg, Sweden


Henrik Zetterberg is a Professor of Neurochemistry at the University of Gothenburg, Sweden, and University College London, UK, and a Clinical Chemist at Sahlgrenska University Hospital in Gothenburg, Sweden. He is Head of the Department of Psychiatry and Neurochemistry at the University of Gothenburg, leads the UK DRI Fluid Biomarker Laboratory at UCL, and is a Key Member of the Hong Kong Center for Neurodegenerative Diseases and a Visiting Professor in the UW Department of Medicine, School of Medicine and Public Health, Madison, Wisconsin. His main research focus and clinical interest are fluid biomarkers for brain diseases, neurodegenerative diseases in particular. He has published more than 1,800 scientific articles and received many awards.

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Brum, W. S., Cullen, N. C., Therriault, J., Janelidze, S., Rahmouni, N., Stevenson, J., Servaes, S., Benedet, A. L., Zimmer, E. R., Stomrud, E., Palmqvist, S., Zetterberg, H., Frisoni, G. B., Ashton, N. J., Blennow, K., Mattsson-Carlgren, N., Rosa-Neto, P., & Hansson, O. A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings, Nature Communications, March 14, 2024, Read More

Johnsson, M., Stenberg, Y. T., Farman, H. H., Blennow, K., Zetterberg, H., Malmeström, C., Sandgren, S., Rosenstein, I., Lycke, J., Axelsson, M., & Novakova, L. Serum neurofilament light for detecting disease activity in individual patients in multiple sclerosis: A 48-week prospective single-center study, Multiple Sclerosis, March 13, 2024, Read More

Nilsson, J., Pichet Binette, A., Palmqvist, S., Brum, W. S., Janelidze, S., Ashton, N. J., Spotorno, N., Stomrud, E., Gobom, J., Zetterberg, H., Brinkmalm, A., Blennow, K., & Hansson, O. Cerebrospinal fluid biomarker panel for synaptic dysfunction in a broad spectrum of neurodegenerative diseases, Brain, February 7, 2024, Read More

Homann, J., Osburg, T., Ohlei, O., Dobricic, V., Deecke, L., Bos, I., Vandenberghe, R., Gabel, S., Scheltens, P., Teunissen, C. E., Engelborghs, S., Frisoni, G., Blin, O., Richardson, J. C., Bordet, R., Lleó, A., Alcolea, D., Popp, J., Clark, C., Peyratout, G., Martinez-Lage, P., Tainta, M., Dobson, R.J.B., Legido-Quigley, C., Sleegers, K., Van Broeckhoven, C., Wittig, M., Franke, A., Lill, C.M., Blennow, K., Zetterberg, H., Lovestone, S., Streffer, J., Kate, M., Vos, S. J. B., Barkhof, F., Visser, P. J., & Bertram, L. Genome-Wide Association Study of Alzheimer’s Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer’s Disease Multimodal Biomarker Discovery Dataset, Frontiers in Aging Neuroscience, March 21, 2022, Read More

Neumann, A., Ohlei, O., Küçükali, F., Bos, I. J., Timsina, J., Vos, S., Prokopenko, D., Tijms, B. M., Andreasson, U., Blennow, K., Vandenberghe, R., Scheltens, P., Teunissen, C. E., Engelborghs, S., Frisoni, G. B., Blin, O., Richardson, J. C., Bordet, R., Lleó, A., Alcolea, D., … EMIF-AD & ADNI study group Multivariate GWAS of Alzheimer’s disease CSF biomarker profiles implies GRIN2D in synaptic functioning, Genome Medicine, October 4, 2023, Read More

Van Egroo, M., Riphagen, J. M., Ashton, N. J., Janelidze, S., Sperling, R. A., Johnson, K. A., Yang, H. S., Bennett, D. A., Blennow, K., Hansson, O., Zetterberg, H., & Jacobs, H. I. L. Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated tau, Molecular Psychiatry, April 5, 2023, Read More

Hansson, O., Blennow, K., Zetterberg, H., & Dage, J. Blood biomarkers for Alzheimer’s disease in clinical practice and trials, Nature Aging, May 18, 2023, Read More

Suárez-Calvet, M., Kleinberger, G., Araque Caballero, M. Á., Brendel, M., Rominger, A., Alcolea, D., Fortea, J., Lleó, A., Blesa, R., Gispert, J. D., Sánchez-Valle, R., Antonell, A., Rami, L., Molinuevo, J. L., Brosseron, F., Traschütz, A., Heneka, M. T., Struyfs, H., Engelborghs, S., Sleegers, K., Van Broeckhove, C., Zetterberg, H., Nellgard, B., Blennow, K., Crispin, A., Ewers, M., & Haass, C. sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer’s disease and associate with neuronal injury markers, EMBO Molecular Medicine, March 3, 2016, Read More

Michno, W., Stringer, K. M., Enzlein, T., Passarelli, M. K., Escrig, S., Vitanova, K., Wood, J., Blennow, K., Zetterberg, H., Meibom, A., Hopf, C., Edwards, F. A., & Hanrieder, J. Following spatial Aβ aggregation dynamics in evolving Alzheimer’s disease pathology by imaging stable isotope labeling kinetics, Science Advances, June 16, 2021, Read More

Wilson, D. M., 3rd, Cookson, M. R., Van Den Bosch, L., Zetterberg, H., Holtzman, D. M., & Dewachter, I. Hallmarks of neurodegenerative diseases, Cell, February 16, 2023, Read More

Huber, H., Blennow, K., Zetterberg, H., Boada, M., Jeromin, A., Weninger, H., Nuñez-Llaves, R., Aguilera, N., Ramis, M., Simrén, J., Nilsson, J., Lantero-Rodriguez, J., Orellana, A., García-Gutiérrez, F., Morató, X., Ashton, N. J., & Montoliu-Gaya, L. Biomarkers of Alzheimer’s disease and neurodegeneration in dried blood spots-A new collection method for remote settings, Alzheimer's & Dementia, January 29, 2024, Read More

Gobom, J., Brinkmalm, A., Brinkmalm, G., Blennow, K., & Zetterberg, H. Alzheimer’s disease biomarker analysis using targeted mass spectrometry, Molecular & Cellular Proteomics, January 20, 2024, Read More

Brum, W. S., Docherty, K. F., Ashton, N. J., Zetterberg, H., Hansson, O., McMurray, J. J. V., & Blennow, K. Effect of Neprilysin Inhibition on Alzheimer Disease Plasma Biomarkers: A Secondary Analysis of a Randomized Clinical Trial, JAMA Neurology, December 18, 2023, Read More