Josh Morganti, Ph.D.

Assistant Professor, Department of Neuroscience, University of Kentucky

Dr. Morganti is an Assistant Professor in the Department of Neuroscience and Sanders Brown Center of Aging at the University of Kentucky. Research in Dr.

Morganti’s lab focuses on understanding the heterogeneity and susceptibility of astrocyte and microglial cell populations in order to provide exciting clues as to the mechanisms underlying brain dysfunction. Approaches in the Morganti lab are geared toward applying multidisciplinary approaches to study the complex heterogeneous inflammatory response of astrocytes and microglia across a  variety of neurodegenerative disease models. Cutting-edge technologies used in the lab include single-cell RNA sequencing (scRNAseq), spatial transcriptomics, fluorescently activated cell sorting (FACS), cell-specific conditional knockout (cKO) models, and bioinformatics.



Related Research:

Apolipoprotein E and Immunometabolism in Alzheimer’s Disease Lance Johnson Josh Morganti Ramon Sun 2022-02-14

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Lee, S., Devanney, N. A., Golden, L. R., Smith, C. T., Schwartz, J. L., Walsh, A. E., Clarke, H. A., Goulding, D. S., Allenger, E. J., Morillo-Segovia, G., Friday, C. M., Gorman, A. A., Hawkinson, T. R., MacLean, S. M., Williams, H. C., Sun, R. C., Morganti, J. M., & Johnson, L. A. APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge, Cell Reports, March 3, 2023, Read More