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Kenneth Pearce, Ph.D.

Professor within the Center for Integrative Chemical Biology and Drug Discovery in the UNC Eshelman School of Pharmacy and Director of the Lead Discovery and Characterization

Kenneth Pearce is a Professor within the Center for Integrative Chemical Biology and Drug Discovery in the UNC Eshelman School of Pharmacy and Director of the Lead Discovery and Characterization. Before joining UNC, Dr. Pearce worked at Genetech and GSK for over 20 years. His work on phage display and nuclear receptors have contributed significantly to both basic science and drug discovery in multiple therapeutic areas. His primary interest and expertise at UNC is application of various methods for conducting early drug and chemical probe discovery research.

Related Research:

Small Molecule Activators of PLC-gamma-2 as Novel Therapeutics for Alzheimer’s Disease Qisheng Zhang John Sondek Kenneth Pearce 2020-12-21

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Project Description Researchers Funding
Small Molecule Activators of PLC-gamma-2 as Novel Therapeutics for Alzheimer’s Disease 2020, 2022

$345,000

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Carr, A. J., Hajicek, N., Tsai, A. P., Acharya, P. P., Hardy, P. B., Meyer, E., Wyss-Coray, T., Pearce, K. H., Sondek, J., & Zhang, Q. A high-throughput assay platform to discover small molecule activators of the phospholipase PLC-γ2 to treat Alzheimer’s disease, The Journal of Biological Chemistry, February 25, 2025, Read More

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