Yingxue Ren, Ph.D.

Assistant Professor, Mayo Clinic Jacksonville


Dr. Yingxue Ren is an Assistant Professor of Biomedical Informatics in the Department of Quantitative Health Sciences at Mayo Clinic Jacksonville. Dr. Ren’s research focuses on developing and applying novel bioinformatics approaches to translational science to help identify novel disease risk factors and therapeutic targets, specifically for neurodegenerative diseases such as Alzheimer’s disease. Dr. Ren’s expertise is omics analysis of disease models, including whole exome and genome sequencing, bulk and single-cell transcriptomics, cell type deconvolution, proteomics, lipidomics, metabolomics, epigenomics, as well as multiomics integration. Dr. Ren’s research will enable the discovery and validation of novel therapeutic targets for the treatment of neurodegenerative diseases.

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Ma, X., Prokopenko, D., Wang, N., Aikawa, T., Choi, Y., Zhang, C., Lei, D., Ren, Y., Kawatani, K., Starling, S. C., Perkerson, R. B., Roy, B., Quintero, A. C., Parsons, T. M., Pan, Y., Li, Z., Wang, M., Bao, H., Han, X., Bu, G., Tanzi, R. E., Kanekiyo, T. Alzheimer’s disease risk ABCA7 p.A696S variant disturbs the microglial response to amyloid pathology in mice, Neurobiology of Disease, January 27, 2025, Read More